Title |
Cytogenetic effect of low dose γ-radiation in Hordeum vulgare seedlings: non-linear dose–effect relationship
|
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Published in |
Radiation and Environmental Biophysics, December 2006
|
DOI | 10.1007/s00411-006-0082-z |
Pubmed ID | |
Authors |
Stanislav A. Geras’kin, Alla A. Oudalova, Jin Kyu Kim, Vladimir G. Dikarev, Nina S. Dikareva |
Abstract |
The induction of chromosome aberrations in Hordeum vulgare germinated seeds was studied after ionizing irradiation with doses in the range of 10-1,000 mGy. The relationship between the frequency of aberrant cells and the absorbed dose was found to be nonlinear. A dose-independent plateau in the dose range from about 50 to 500 mGy was observed, where the level of cytogenetic damage was significantly different from the spontaneous level. The comparison of the goodness of the experimental data fitting with mathematical models of different complexity, using the most common quantitative criteria, demonstrated the advantage of a piecewise linear model over linear and polynomial models in approximating the frequency of cytogenetical disturbances. The results of the study support the hypothesis of indirect mechanisms of mutagenesis induced by low doses. Fundamental and applied implications of these findings are discussed. |
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Japan | 3 | 60% |
Unknown | 2 | 40% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 5 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 18 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 5 | 28% |
Student > Master | 3 | 17% |
Professor | 2 | 11% |
Student > Doctoral Student | 1 | 6% |
Student > Ph. D. Student | 1 | 6% |
Other | 2 | 11% |
Unknown | 4 | 22% |
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Environmental Science | 4 | 22% |
Biochemistry, Genetics and Molecular Biology | 1 | 6% |
Chemistry | 1 | 6% |
Engineering | 1 | 6% |
Other | 0 | 0% |
Unknown | 3 | 17% |