| Title |
Are There Enhanced MBP Autoantibodies in Autism?
|
|---|---|
| Published in |
Journal of Autism and Developmental Disorders, June 2007
|
| DOI | 10.1007/s10803-007-0400-6 |
| Pubmed ID | |
| Authors |
Jane E. Libbey, Hilary H. Coon, Nikki J. Kirkman, Thayne L. Sweeten, Judith N. Miller, Edward K. Stevenson, Janet E. Lainhart, William M. McMahon, Robert S. Fujinami |
| Abstract |
Autoantibodies to central nervous system antigens, such as myelin basic protein (MBP), may play a role in autism. We measured autoantibody titers to MBP in children with autism, both classic onset and regressive onset forms, controls (healthy age- and gender-matched) and individuals with Tourette syndrome via enzyme-linked immunosorbent assays. We found a significant difference in autoantibody titers to MBP, not accounted for by age or medication, between Tourette and classic autism (both significantly lower) when compared to regressive autism, but not when compared to controls. Autoantibody responses against MBP are unlikely to play a pathogenic role in autism. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 45 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 7 | 16% |
| Professor | 6 | 13% |
| Professor > Associate Professor | 5 | 11% |
| Student > Bachelor | 4 | 9% |
| Student > Postgraduate | 4 | 9% |
| Other | 12 | 27% |
| Unknown | 7 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 10 | 22% |
| Medicine and Dentistry | 9 | 20% |
| Agricultural and Biological Sciences | 7 | 16% |
| Biochemistry, Genetics and Molecular Biology | 4 | 9% |
| Neuroscience | 4 | 9% |
| Other | 2 | 4% |
| Unknown | 9 | 20% |
Attention Score in Context
This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 November 2019.
All research outputs
#4,565,164
of 25,301,208 outputs
Outputs from Journal of Autism and Developmental Disorders
#1,791
of 5,443 outputs
Outputs of similar age
#13,018
of 76,799 outputs
Outputs of similar age from Journal of Autism and Developmental Disorders
#4
of 12 outputs
Altmetric has tracked 25,301,208 research outputs across all sources so far. Compared to these this one has done well and is in the 81st percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 5,443 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.2. This one has gotten more attention than average, scoring higher than 66% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 76,799 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 83% of its contemporaries.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 75% of its contemporaries.