| Title |
Methyl-triclosan and triclosan impact embryonic development of Danio rerio and Paracentrotus lividus
|
|---|---|
| Published in |
Ecotoxicology, February 2017
|
| DOI | 10.1007/s10646-017-1778-3 |
| Pubmed ID | |
| Authors |
Sofia Macedo, Tiago Torres, Miguel M. Santos |
| Abstract |
The presence of emerging pollutants in the environment is of major concern not only because of the potential negative impact in human health, but also due to the potential toxicity to non-target organisms. Within the personal and care products (PCPs), the disinfectant Triclosan (TCS) is one of the most concerning compounds. Once in the wastewater treatment plants (WWTPs), a small part of TCS can be biotransformed into a more persistent by-product: methyl-triclosan (M-TCS). Although several studies have focused on the occurrence of this compound in the water systems, the information on its toxicity to aquatic organisms is very limited. Here, we used embryo bioassays with two aquatic model animals to improve risk assessment of M-TCS; zebrafish (Danio rerio) embryo bioassays run up to 144 h post fertilization (hpf) and sea urchin (Paracentrotus lividus) up to 48 hpf, following established protocols. M-TCS and TCS exhibited similar toxicity to zebrafish with a NOEC of 160 µg/L. In contrast, M-TCS induced a delay in the development of the sea urchin larvae at all tested concentrations (1-1000 µg/L), whereas NOEC of TCS for P. lividus embryos was 40 µg/L. Overall, given the reported effects of M-TCS in the close range of environmentally relevant concentrations, and considering the low degradation rate and tendency to bioaccumulation (logKow: 5.2), further studies are warrant to better characterize the risk of this TCS metabolite to aquatic organisms. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 64 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Portugal | 1 | 2% |
| Unknown | 63 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 10 | 16% |
| Student > Ph. D. Student | 9 | 14% |
| Student > Master | 6 | 9% |
| Student > Postgraduate | 4 | 6% |
| Professor > Associate Professor | 4 | 6% |
| Other | 10 | 16% |
| Unknown | 21 | 33% |
| Readers by discipline | Count | As % |
|---|---|---|
| Environmental Science | 14 | 22% |
| Agricultural and Biological Sciences | 11 | 17% |
| Biochemistry, Genetics and Molecular Biology | 5 | 8% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 3% |
| Medicine and Dentistry | 2 | 3% |
| Other | 7 | 11% |
| Unknown | 23 | 36% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 October 2023.
All research outputs
#7,099,990
of 24,682,395 outputs
Outputs from Ecotoxicology
#242
of 1,535 outputs
Outputs of similar age
#108,483
of 316,593 outputs
Outputs of similar age from Ecotoxicology
#8
of 42 outputs
Altmetric has tracked 24,682,395 research outputs across all sources so far. This one has received more attention than most of these and is in the 69th percentile.
So far Altmetric has tracked 1,535 research outputs from this source. They receive a mean Attention Score of 3.6. This one has done well, scoring higher than 83% of its peers.
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We're also able to compare this research output to 42 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 83% of its contemporaries.