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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Genetic insights into common pathways and complex relationships among immune-mediated diseases
|
|---|---|
| Published in |
Nature Reviews Genetics, August 2013
|
| DOI | 10.1038/nrg3502 |
| Pubmed ID | |
| Authors |
Miles Parkes, Adrian Cortes, David A. van Heel, Matthew A. Brown |
| Abstract |
Shared aetiopathogenic factors among immune-mediated diseases have long been suggested by their co-familiality and co-occurrence, and molecular support has been provided by analysis of human leukocyte antigen (HLA) haplotypes and genome-wide association studies. The interrelationships can now be better appreciated following the genotyping of large immune disease sample sets on a shared SNP array: the 'Immunochip'. Here, we systematically analyse loci shared among major immune-mediated diseases. This reveals that several diseases share multiple susceptibility loci, but there are many nuances. The most associated variant at a given locus frequently differs and, even when shared, the same allele often has opposite associations. Interestingly, risk alleles conferring the largest effect sizes are usually disease-specific. These factors help to explain why early evidence of extensive 'sharing' is not always reflected in epidemiological overlap. |
X Demographics
The data shown below were collected from the profiles of 14 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 5 | 36% |
| United States | 3 | 21% |
| Spain | 1 | 7% |
| Mexico | 1 | 7% |
| Unknown | 4 | 29% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 8 | 57% |
| Scientists | 5 | 36% |
| Practitioners (doctors, other healthcare professionals) | 1 | 7% |
Mendeley readers
The data shown below were compiled from readership statistics for 592 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 12 | 2% |
| United Kingdom | 6 | 1% |
| Germany | 5 | <1% |
| Spain | 2 | <1% |
| Korea, Republic of | 1 | <1% |
| Italy | 1 | <1% |
| Netherlands | 1 | <1% |
| Austria | 1 | <1% |
| Australia | 1 | <1% |
| Other | 6 | 1% |
| Unknown | 556 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 143 | 24% |
| Researcher | 143 | 24% |
| Student > Master | 47 | 8% |
| Student > Bachelor | 44 | 7% |
| Professor > Associate Professor | 33 | 6% |
| Other | 100 | 17% |
| Unknown | 82 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 191 | 32% |
| Medicine and Dentistry | 104 | 18% |
| Biochemistry, Genetics and Molecular Biology | 97 | 16% |
| Immunology and Microbiology | 41 | 7% |
| Computer Science | 13 | 2% |
| Other | 45 | 8% |
| Unknown | 101 | 17% |
Attention Score in Context
This research output has an Altmetric Attention Score of 21. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 June 2019.
All research outputs
#1,518,817
of 22,715,151 outputs
Outputs from Nature Reviews Genetics
#731
of 2,583 outputs
Outputs of similar age
#14,018
of 197,230 outputs
Outputs of similar age from Nature Reviews Genetics
#9
of 57 outputs
Altmetric has tracked 22,715,151 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,583 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 30.1. This one has gotten more attention than average, scoring higher than 71% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 197,230 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 57 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 84% of its contemporaries.