Title |
Protein Kinase Cδ Deficiency Causes Mendelian Systemic Lupus Erythematosus With B Cell‐Defective Apoptosis and Hyperproliferation
|
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Published in |
Arthritis & Rheumatism, July 2013
|
DOI | 10.1002/art.38008 |
Pubmed ID | |
Authors |
Alexandre Belot, Paul R. Kasher, Eleanor W. Trotter, Anne‐Perrine Foray, Anne‐Laure Debaud, Gillian I. Rice, Marcin Szynkiewicz, Marie‐Therese Zabot, Isabelle Rouvet, Sanjeev S. Bhaskar, Sarah B. Daly, Jonathan E. Dickerson, Josephine Mayer, James O'Sullivan, Laurent Juillard, Jill E. Urquhart, Shameem Fawdar, Anna A. Marusiak, Natalie Stephenson, Bohdan Waszkowycz, Michael W. Beresford, Leslie G. Biesecker, Graeme C. M. Black, Céline René, Jean‐François Eliaou, Nicole Fabien, Bruno Ranchin, Pierre Cochat, Patrick M. Gaffney, Flore Rozenberg, Pierre Lebon, Christophe Malcus, Yanick J. Crow, John Brognard, Nathalie Bonnefoy |
Abstract |
Systemic lupus erythematosus (SLE) is a prototype autoimmune disease that is assumed to occur via a complex interplay of environmental and genetic factors. Rare causes of monogenic SLE have been described, providing unique insights into fundamental mechanisms of immune tolerance. The aim of this study was to identify the cause of an autosomal-recessive form of SLE. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Scientists | 1 | 50% |
Practitioners (doctors, other healthcare professionals) | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Denmark | 1 | 1% |
Unknown | 88 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 18 | 20% |
Researcher | 10 | 11% |
Student > Master | 9 | 10% |
Student > Bachelor | 7 | 8% |
Other | 6 | 7% |
Other | 20 | 22% |
Unknown | 19 | 21% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 19 | 21% |
Biochemistry, Genetics and Molecular Biology | 18 | 20% |
Immunology and Microbiology | 15 | 17% |
Agricultural and Biological Sciences | 8 | 9% |
Economics, Econometrics and Finance | 1 | 1% |
Other | 5 | 6% |
Unknown | 23 | 26% |