| Title |
Mitochondrial respiratory chain dysfunction modulates metalloproteases -1, -3 and -13 in human normal chondrocytes in culture
|
|---|---|
| Published in |
BMC Musculoskeletal Disorders, August 2013
|
| DOI | 10.1186/1471-2474-14-235 |
| Pubmed ID | |
| Authors |
Berta Cillero-Pastor, Ignacio Rego-Pérez, Natividad Oreiro, Carlos Fernandez-Lopez, Francisco J Blanco |
| Abstract |
Mitochondrion has an important role in the osteoarthritis (OA) pathology. We have previously demonstrated that the alteration of the mitochondrial respiratory chain (MRC) contributes to the inflammatory response of the chondrocyte. However its implication in the process of cartilage destruction is not well understood yet. In this study we have investigated the relationship between the MRC dysfunction and the regulation of metalloproteases (MMPs) in human normal chondrocytes in culture. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 48 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 2% |
| Portugal | 1 | 2% |
| Unknown | 46 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 9 | 19% |
| Student > Doctoral Student | 6 | 13% |
| Student > Master | 5 | 10% |
| Student > Bachelor | 4 | 8% |
| Other | 3 | 6% |
| Other | 9 | 19% |
| Unknown | 12 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 10 | 21% |
| Biochemistry, Genetics and Molecular Biology | 5 | 10% |
| Medicine and Dentistry | 4 | 8% |
| Engineering | 3 | 6% |
| Nursing and Health Professions | 2 | 4% |
| Other | 7 | 15% |
| Unknown | 17 | 35% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 August 2013.
All research outputs
#18,342,133
of 22,715,151 outputs
Outputs from BMC Musculoskeletal Disorders
#3,115
of 4,031 outputs
Outputs of similar age
#147,746
of 197,311 outputs
Outputs of similar age from BMC Musculoskeletal Disorders
#77
of 83 outputs
Altmetric has tracked 22,715,151 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,031 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.0. This one is in the 10th percentile – i.e., 10% of its peers scored the same or lower than it.
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We're also able to compare this research output to 83 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.