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X Demographics
Mendeley readers
Attention Score in Context
| Title |
The lysosome: from waste bag to potential therapeutic target
|
|---|---|
| Published in |
Journal of Molecular Cell Biology, August 2013
|
| DOI | 10.1093/jmcb/mjt022 |
| Pubmed ID | |
| Authors |
Hanna Appelqvist, Petra Wäster, Katarina Kågedal, Karin Öllinger |
| Abstract |
Lysosomes are ubiquitous membrane-bound intracellular organelles with an acidic interior. They are central for degradation and recycling of macromolecules delivered by endocytosis, phagocytosis, and autophagy. In contrast to the rather simplified view of lysosomes as waste bags, nowadays lysosomes are recognized as advanced organelles involved in many cellular processes and are considered crucial regulators of cell homeostasis. The function of lysosomes is critically dependent on soluble lysosomal hydrolases (e.g. cathepsins) as well as lysosomal membrane proteins (e.g. lysosome-associated membrane proteins). This review focuses on lysosomal involvement in digestion of intra- and extracellular material, plasma membrane repair, cholesterol homeostasis, and cell death. Regulation of lysosomal biogenesis and function via the transcription factor EB (TFEB) will also be discussed. In addition, lysosomal contribution to diseases, including lysosomal storage disorders, neurodegenerative disorders, cancer, and cardiovascular diseases, is presented. |
X Demographics
The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 1 | 20% |
| United States | 1 | 20% |
| Unknown | 3 | 60% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 60% |
| Scientists | 2 | 40% |
Mendeley readers
The data shown below were compiled from readership statistics for 698 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 3 | <1% |
| United States | 3 | <1% |
| United Kingdom | 3 | <1% |
| Brazil | 2 | <1% |
| Russia | 2 | <1% |
| India | 2 | <1% |
| Netherlands | 1 | <1% |
| Canada | 1 | <1% |
| Italy | 1 | <1% |
| Other | 4 | <1% |
| Unknown | 676 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 166 | 24% |
| Researcher | 113 | 16% |
| Student > Bachelor | 93 | 13% |
| Student > Master | 89 | 13% |
| Student > Doctoral Student | 34 | 5% |
| Other | 91 | 13% |
| Unknown | 112 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 193 | 28% |
| Biochemistry, Genetics and Molecular Biology | 176 | 25% |
| Medicine and Dentistry | 55 | 8% |
| Chemistry | 42 | 6% |
| Pharmacology, Toxicology and Pharmaceutical Science | 25 | 4% |
| Other | 75 | 11% |
| Unknown | 132 | 19% |
Attention Score in Context
This research output has an Altmetric Attention Score of 31. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 February 2024.
All research outputs
#1,300,138
of 26,017,215 outputs
Outputs from Journal of Molecular Cell Biology
#17
of 657 outputs
Outputs of similar age
#10,877
of 214,310 outputs
Outputs of similar age from Journal of Molecular Cell Biology
#1
of 10 outputs
Altmetric has tracked 26,017,215 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 657 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.0. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 214,310 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them