Title |
Cigarette smoking and prostate cancer-specific mortality following diagnosis in middle-aged men
|
---|---|
Published in |
Cancer Causes & Control, September 2007
|
DOI | 10.1007/s10552-007-9066-9 |
Pubmed ID | |
Authors |
Zhihong Gong, Ilir Agalliu, Daniel W. Lin, Janet L. Stanford, Alan R. Kristal |
Abstract |
The aim of this study was to examine associations of smoking at the time of diagnosis with the risk of prostate cancer death in a population-based cohort of men with prostate cancer. Data were from 752 prostate cancer patients aged 40-64 years, who were enrolled in a case-control study and under long-term follow-up for mortality. Cox proportional hazards models were used to estimate hazard ratios (HR) and 95% confidence intervals (CI) for associations between smoking and prostate cancer-specific and other cause mortality. Compared to never smoking, smoking at the time of diagnosis was associated with a significant increase in risk of prostate cancer-specific mortality. After controlling for demographic characteristics, Gleason grade, stage at diagnosis, and primary treatment, the HR was 2.66 (95% CI: 1.10-6.43). Smoking at the time of diagnosis, independent of key clinical prognostic factors, is associated with an increased risk of prostate cancer death. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 22 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 6 | 27% |
Student > Doctoral Student | 3 | 14% |
Professor | 3 | 14% |
Other | 2 | 9% |
Student > Master | 2 | 9% |
Other | 4 | 18% |
Unknown | 2 | 9% |
Readers by discipline | Count | As % |
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Environmental Science | 1 | 5% |
Psychology | 1 | 5% |
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Other | 2 | 9% |
Unknown | 3 | 14% |