Title |
Designing pharmaceutical trials for sarcopenia in frail older adults: EU/US task force recommendations
|
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Published in |
The journal of nutrition, health & aging, August 2013
|
DOI | 10.1007/s12603-013-0362-7 |
Pubmed ID | |
Authors |
B. Vellas, M. Pahor, T. Manini, D. Rooks, J.M. Guralnik, J. Morley, S. Studenski, W. Evans, C. Asbrand, R. Fariello, S. Pereira, Y. Rolland, G. Abellan Van Kan, M. Cesari, W.M.C. Chumlea, R. Fielding |
Abstract |
An international task force of academic and industry leaders in sarcopenia research met on December 5, 2012 in Orlando, Florida to develop guidelines for designing and executing randomized clinical trials of sarcopenia treatments. The Task Force reviewed results from previous trials in related disease areas to extract lessons relevant to future sarcopenia trials, including practical issues regarding the design and conduct of trials in elderly populations, the definition of appropriate target populations, and the selection of screening tools, outcome measures, and biomarkers. They discussed regulatory issues, the challenges posed by trials of different types of interventions, and the need for standardization and harmonization. The Task Force concluded with recommendations for advancing the field toward better clinical trials. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Scientists | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 62 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 11 | 18% |
Student > Master | 10 | 16% |
Researcher | 7 | 11% |
Student > Bachelor | 6 | 10% |
Professor | 3 | 5% |
Other | 8 | 13% |
Unknown | 17 | 27% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 18 | 29% |
Nursing and Health Professions | 8 | 13% |
Sports and Recreations | 5 | 8% |
Agricultural and Biological Sciences | 2 | 3% |
Neuroscience | 2 | 3% |
Other | 8 | 13% |
Unknown | 19 | 31% |