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A Protocol for the Pharmacokinetics of Enteric Coated Mycophenolate Sodium in Lupus Nephritis (POEMSLUN): an open-label, randomised controlled trial

Overview of attention for article published in BMJ Open, August 2013
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Title
A Protocol for the Pharmacokinetics of Enteric Coated Mycophenolate Sodium in Lupus Nephritis (POEMSLUN): an open-label, randomised controlled trial
Published in
BMJ Open, August 2013
DOI 10.1136/bmjopen-2013-003511
Pubmed ID
Authors

Dwarakanathan Ranganathan, George T John, Helen Healy, Matthew J Roberts, Robert G Fassett, Jeffrey Lipman, Paul Kubler, Jacobus Ungerer, Brett C McWhinney, Aaron Lim, Megan Purvey, Reza Reyaldeen, Jason A Roberts

Abstract

Mycophenolate sodium, an enteric-coated tablet (EC-MPS), is as effective and safe as mycophenolate mofetil (MMF) in preventing transplant rejection. EC-MPS and MMF improve the outcome of severe lupus nephritis (LN) and have fewer side effects than pulsed intravenous cyclophosphamide. Blood concentrations of mycophenolic acid (MPA), the active metabolite of EC-MPS, vary between participants despite fixed dosing. Interpatient variability has been studied in transplantation, but not well documented in LN. The relationship between MPA concentration and its clinical effect on LN has not been described.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 22 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 5%
Unknown 21 95%

Demographic breakdown

Readers by professional status Count As %
Student > Doctoral Student 3 14%
Student > Ph. D. Student 2 9%
Professor > Associate Professor 2 9%
Professor 2 9%
Student > Master 2 9%
Other 6 27%
Unknown 5 23%
Readers by discipline Count As %
Medicine and Dentistry 9 41%
Biochemistry, Genetics and Molecular Biology 2 9%
Unspecified 1 5%
Nursing and Health Professions 1 5%
Pharmacology, Toxicology and Pharmaceutical Science 1 5%
Other 2 9%
Unknown 6 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 September 2013.
All research outputs
#20,656,820
of 25,374,917 outputs
Outputs from BMJ Open
#21,929
of 25,589 outputs
Outputs of similar age
#158,819
of 208,928 outputs
Outputs of similar age from BMJ Open
#240
of 245 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 25,589 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 18.2. This one is in the 7th percentile – i.e., 7% of its peers scored the same or lower than it.
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We're also able to compare this research output to 245 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.