Title |
2-(4-Iodo-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine (25I-NBOMe): Clinical Case with Unique Confirmatory Testing
|
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Published in |
Journal of Medical Toxicology, July 2013
|
DOI | 10.1007/s13181-013-0314-y |
Pubmed ID | |
Authors |
Samuel J. Stellpflug, Samantha E. Kealey, Cullen B. Hegarty, Gregory C. Janis |
Abstract |
2C designer drugs have been in use since the 1970s, but new drugs continue to develop from substitutions to the base phenethylamine structure. This creates new clinical profiles and difficulty with laboratory confirmation. 2-(4-Iodo-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine (25I-NBOMe) is a relatively new 2C drug that is more potent than structural 2C analogs; exposure reports are rare. Testing for 2C drugs is developing; specific testing for new analogs such as 25I-NBOMe is a challenge. These drugs do not reliably trigger a positive result on rapid drug immunoassays. Additionally, most facilities with confirmatory testing capabilities will not identify 25I-NBOMe; methods for detecting 25I-NBOMe in biological samples have not been clearly described nor have optimal metabolic targets for detecting 25I-NBOMe ingestion. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United Kingdom | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 1 | 2% |
South Africa | 1 | 2% |
Switzerland | 1 | 2% |
Brazil | 1 | 2% |
Unknown | 59 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
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Other | 11 | 17% |
Student > Master | 11 | 17% |
Student > Ph. D. Student | 8 | 13% |
Student > Bachelor | 7 | 11% |
Researcher | 6 | 10% |
Other | 12 | 19% |
Unknown | 8 | 13% |
Readers by discipline | Count | As % |
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Chemistry | 16 | 25% |
Medicine and Dentistry | 16 | 25% |
Pharmacology, Toxicology and Pharmaceutical Science | 7 | 11% |
Psychology | 4 | 6% |
Neuroscience | 3 | 5% |
Other | 8 | 13% |
Unknown | 9 | 14% |