| Title |
The Sympathetic Nervous System and Pain
|
|---|---|
| Published in |
NeuroMolecular Medicine, November 2007
|
| DOI | 10.1007/s12017-007-8018-6 |
| Pubmed ID | |
| Authors |
Tanja Schlereth, Frank Birklein |
| Abstract |
The sympathetic nervous system (SNS) and pain interact on many levels of the neuraxis. In healthy subjects, activation of the SNS in the brain usually suppresses pain mainly by descending inhibition of nociceptive transmission in the spinal cord. Furthermore, some experimental data even suggest that the SNS might control peripheral inflammation and nociceptive activation. However, even subtle changes in pathophysiology can dramatically change the effect of SNS on pain, and vice versa. In the periphery, inflammation or nociceptive activation is enhanced, spinal descending inhibition is reversed to spinal facilitation, and finally the awareness of all these changes will induce anxiety, which furthermore amplifies pain perception, affects pain behavior, and depresses mood. Unraveling the detailed molecular mechanisms of how this interaction of SNS and pain is established in health and disease will help us to treat pain more successfully in the future. |
X Demographics
The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Canada | 2 | 29% |
| India | 1 | 14% |
| Unknown | 4 | 57% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 5 | 71% |
| Scientists | 1 | 14% |
| Practitioners (doctors, other healthcare professionals) | 1 | 14% |
Mendeley readers
The data shown below were compiled from readership statistics for 282 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | <1% |
| Germany | 1 | <1% |
| Italy | 1 | <1% |
| Portugal | 1 | <1% |
| United Kingdom | 1 | <1% |
| Sweden | 1 | <1% |
| Venezuela, Bolivarian Republic of | 1 | <1% |
| Canada | 1 | <1% |
| Unknown | 273 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 39 | 14% |
| Student > Ph. D. Student | 35 | 12% |
| Student > Bachelor | 34 | 12% |
| Other | 25 | 9% |
| Student > Doctoral Student | 24 | 9% |
| Other | 61 | 22% |
| Unknown | 64 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 81 | 29% |
| Nursing and Health Professions | 28 | 10% |
| Psychology | 18 | 6% |
| Agricultural and Biological Sciences | 16 | 6% |
| Neuroscience | 13 | 5% |
| Other | 51 | 18% |
| Unknown | 75 | 27% |
Attention Score in Context
This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 January 2022.
All research outputs
#3,985,316
of 22,867,327 outputs
Outputs from NeuroMolecular Medicine
#95
of 447 outputs
Outputs of similar age
#12,319
of 77,872 outputs
Outputs of similar age from NeuroMolecular Medicine
#1
of 5 outputs
Altmetric has tracked 22,867,327 research outputs across all sources so far. Compared to these this one has done well and is in the 82nd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 447 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.3. This one has done well, scoring higher than 78% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 77,872 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 84% of its contemporaries.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them