| Title |
Pharmacological and nonpharmacological prevention of fentanyl-induced cough: a meta-analysis
|
|---|---|
| Published in |
Journal of Anesthesia, August 2013
|
| DOI | 10.1007/s00540-013-1695-4 |
| Pubmed ID | |
| Authors |
Ji Eun Kim, Sang Kee Min, Yun Jeong Chae, Yeon Ju Lee, Bong Ki Moon, Jong Yeop Kim |
| Abstract |
Fentanyl-induced cough (FIC) is often observed after intravenous bolus administration of fentanyl during anesthesia induction. This meta-analysis assessed the efficacy of pharmacological and nonpharmacological interventions to reduce the incidence of FIC. We searched for randomized controlled trials comparing pharmacological or nonpharmacological interventions with controls to prevent FIC; we included 28 studies retrieved from PubMed, Embase, and Cochrane Library. Overall incidence of FIC was approximately 31 %. Lidocaine [odds ratio (OR) = 0.29, 95 % confidence interval (CI) 0.21-0.39], N-methyl-D-aspartate (NMDA) receptor antagonists (OR 0.09, 95 % CI 0.02-0.42), propofol (OR 0.07, 95 % CI 0.01-0.36), α2 agonists (OR 0.32, 95 % CI 0.21-0.48), β2 agonists (OR 0.10, 95 % CI 0.03-0.30), fentanyl priming (OR 0.33, 95 % CI 0.19-0.56), and slow injection of fentanyl (OR 0.25, 95 % CI 0.11-0.58)] were effective in decreasing the incidence of FIC, whereas atropine (OR 1.10, 95 % CI 0.58-2.11) and benzodiazepines (OR 2.04, 95 % CI 1.33-3.13) were not effective. This meta-analysis found that lidocaine, NMDA receptor antagonists, propofol, α2 agonists, β2 agonists, and priming dose of fentanyl were effective in preventing FIC, but atropine and benzodiazepines were not. Slow injection of fentanyl was effective in preventing FIC, but results depend on the speed of administration. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 3 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 67% |
| Practitioners (doctors, other healthcare professionals) | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 27 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Brazil | 2 | 7% |
| Korea, Republic of | 1 | 4% |
| Unknown | 24 | 89% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 4 | 15% |
| Student > Doctoral Student | 4 | 15% |
| Student > Bachelor | 4 | 15% |
| Other | 3 | 11% |
| Student > Postgraduate | 2 | 7% |
| Other | 4 | 15% |
| Unknown | 6 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 12 | 44% |
| Pharmacology, Toxicology and Pharmaceutical Science | 5 | 19% |
| Materials Science | 1 | 4% |
| Psychology | 1 | 4% |
| Unknown | 8 | 30% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 August 2013.
All research outputs
#15,025,075
of 23,878,777 outputs
Outputs from Journal of Anesthesia
#389
of 852 outputs
Outputs of similar age
#114,959
of 202,613 outputs
Outputs of similar age from Journal of Anesthesia
#6
of 13 outputs
Altmetric has tracked 23,878,777 research outputs across all sources so far. This one is in the 34th percentile – i.e., 34% of other outputs scored the same or lower than it.
So far Altmetric has tracked 852 research outputs from this source. They receive a mean Attention Score of 3.3. This one has gotten more attention than average, scoring higher than 50% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 202,613 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 61% of its contemporaries.