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A patient with both narcolepsy and multiple sclerosis in association with Pandemrix vaccination

Overview of attention for article published in Journal of the Neurological Sciences, July 2012
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Citations

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Title
A patient with both narcolepsy and multiple sclerosis in association with Pandemrix vaccination
Published in
Journal of the Neurological Sciences, July 2012
DOI 10.1016/j.jns.2012.07.025
Pubmed ID
Authors

Magnus Vrethem, Kristina Malmgren, Jonas Lindh

Abstract

Narcolepsy with cataplexy is caused by a selective loss of hypocretin-producing neurons, but symptomatic narcolepsy can also result from hypothalamic and brainstem lesions caused by multiple sclerosis (MS). We report a previously healthy man who developed clinical and laboratory verified narcolepsy without having any indication of hypothalamic lesions and MS after vaccination against the influenza H1N1 with Pandemrix. HLA typing showed both DRB1*15:01, associated with MS and DQB1*06:02, associated with narcolepsy. The genetic susceptibility in this patient makes it tempting to speculate upon an immune-mediated mechanism and a common etiology for both diseases in this patient.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 50 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 2%
United States 1 2%
Germany 1 2%
Unknown 47 94%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 9 18%
Other 8 16%
Researcher 7 14%
Student > Master 7 14%
Student > Postgraduate 3 6%
Other 9 18%
Unknown 7 14%
Readers by discipline Count As %
Medicine and Dentistry 20 40%
Neuroscience 4 8%
Agricultural and Biological Sciences 4 8%
Psychology 3 6%
Immunology and Microbiology 2 4%
Other 6 12%
Unknown 11 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 October 2015.
All research outputs
#19,944,994
of 25,374,647 outputs
Outputs from Journal of the Neurological Sciences
#4,141
of 5,251 outputs
Outputs of similar age
#134,879
of 178,799 outputs
Outputs of similar age from Journal of the Neurological Sciences
#26
of 38 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,251 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.3. This one is in the 18th percentile – i.e., 18% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 178,799 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 21st percentile – i.e., 21% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 38 others from the same source and published within six weeks on either side of this one. This one is in the 31st percentile – i.e., 31% of its contemporaries scored the same or lower than it.