Title |
Fate choice of post-natal mesoderm progenitors: skeletal versus cardiac muscle plasticity
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Published in |
Cellular and Molecular Life Sciences, August 2013
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DOI | 10.1007/s00018-013-1445-7 |
Pubmed ID | |
Authors |
Domiziana Costamagna, Mattia Quattrocelli, Robin Duelen, Vardine Sahakyan, Ilaria Perini, Giacomo Palazzolo, Maurilio Sampaolesi |
Abstract |
Regenerative medicine for skeletal and cardiac muscles still constitutes a fascinating and ambitious frontier. In this perspective, understanding the possibilities of intrinsic cell plasticity, present in post-natal muscles, is vital to define and improve novel therapeutic strategies for acute and chronic diseases. In addition, many somatic stem cells are now crossing the boundaries of basic/translational research to enter the first clinical trials. However, it is still an open question whether a lineage switch between skeletal and cardiac adult myogenesis is possible. Therefore, this review focuses on resident somatic stem cells of post-natal skeletal and cardiac muscles and their plastic potential toward the two lineages. Furthermore, examples of myogenic lineage switch in adult stem cells are also reported and discussed. |
X Demographics
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United States | 1 | 100% |
Demographic breakdown
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Scientists | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 30 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 8 | 27% |
Student > Ph. D. Student | 7 | 23% |
Student > Master | 4 | 13% |
Professor | 2 | 7% |
Student > Bachelor | 2 | 7% |
Other | 0 | 0% |
Unknown | 7 | 23% |
Readers by discipline | Count | As % |
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Biochemistry, Genetics and Molecular Biology | 8 | 27% |
Agricultural and Biological Sciences | 8 | 27% |
Medicine and Dentistry | 4 | 13% |
Neuroscience | 1 | 3% |
Design | 1 | 3% |
Other | 0 | 0% |
Unknown | 8 | 27% |