Title |
Pediatric Allergic Rhinitis and Asthma: Can the March be Halted?
|
---|---|
Published in |
Pediatric Drugs, August 2013
|
DOI | 10.1007/s40272-013-0043-3 |
Pubmed ID | |
Authors |
Olympia A. Tsilochristou, Nikolaos Douladiris, Michael Makris, Nikolaos G. Papadopoulos |
Abstract |
The strong epidemiologic and pathophysiologic link between allergic rhinitis (AR) and asthma has led to the concept of 'united airways disease' or 'respiratory allergy', implying that allergy, in its widest sense, underlies this clinical syndrome. Progression from AR to asthma is frequent and part of the 'atopic march'. Since pediatric immune responses are more adaptable and therefore may be more amenable to treatment, interventions at early childhood are characterized by a higher chance to affect the natural history of respiratory allergy. Although current treatments are quite effective in alleviating respiratory allergy symptoms, it has proven much more difficult to confirm any influence on the progression of the disease. Much more promising is the field of specific allergen immunotherapy, where current evidence, although not yet of ideal robustness, points towards a disease-modifying effect. In addition, newer or emerging, possibly more effective or more targeted interventions are promising in the preventive sense. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Argentina | 1 | 17% |
Unknown | 5 | 83% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 5 | 83% |
Scientists | 1 | 17% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Japan | 1 | 2% |
Germany | 1 | 2% |
Unknown | 48 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 10 | 20% |
Other | 6 | 12% |
Student > Doctoral Student | 5 | 10% |
Student > Master | 5 | 10% |
Professor > Associate Professor | 4 | 8% |
Other | 10 | 20% |
Unknown | 10 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 27 | 54% |
Agricultural and Biological Sciences | 4 | 8% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 4% |
Biochemistry, Genetics and Molecular Biology | 2 | 4% |
Environmental Science | 1 | 2% |
Other | 4 | 8% |
Unknown | 10 | 20% |