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Cardiac Glycosides 1785–1985

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Cover of 'Cardiac Glycosides 1785–1985'

Table of Contents

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    Book Overview
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    Chapter 1 William Withering — The man and his work
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    Chapter 2 Fruitful routes and blind alleys taken by digitalis therapy since its introduction by Withering
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    Chapter 3 Therapeutic use of digitalis until the time of William Withering
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    Chapter 4 The function of Na+,K+-ATPase and its importance for drug action
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    Chapter 5 Structural studies on the cardiac glycoside receptor
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    Chapter 6 Isoenzymes of Na,K-ATPase identified by pyrithiamin
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    Chapter 7 Interaction of cardiac glycosides with Na/K-ATPase in intact myocardium
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    Chapter 8 The human red blood cell: A model for ouabain receptor regulation in the heart?
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    Chapter 9 Binding and release of ouabain at low Mg2+ in reconstituted human red blood cell ghosts
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    Chapter 10 The ouabain receptor in the myocardium and conduction system of the sheep heart
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    Chapter 11 Electrophysiological effects of cardiac glycosides
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    Chapter 12 Electrophysiological assay of glycoside-induced sodium pump inhibition in isolated sheep heart Purkinje fibres at the onset of toxicity
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    Chapter 13 Rat cardiac hypertrophy: contribution of heteregeneous digitalis receptor forms
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    Chapter 14 Digitalis receptors in normal and hypertrophied rat hearts. Differential effects of a Ca2+ free perfusion
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    Chapter 15 Biphasic contractile response to ouabain: Species specific? Calcium dependent? Altered sensitivity?
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    Chapter 16 The influence of α-tocopherol-nicotinate (Renascin®) on cardiac glycoside effects
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    Chapter 17 On the connection between cardiac glycosides and calcium action
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    Chapter 18 Biochemical basis for the targeted synthesis of cardiac glycosides with selective action
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    Chapter 19 The “endogenous cardiac glycoside”
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    Chapter 20 Endogenous digitalis, cardiodigin and other regulators of the sodium pump
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    Chapter 21 Digitalis-like factors in plasma of healthy human adults
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    Chapter 22 A Na+,K+-ATPase inhibitor isolated from pig kidney
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    Chapter 23 Cardiac glycoside-like effects of a bufadienolide extracted from Kalanchoe Daigremontiana
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    Chapter 24 Positive inotropic agents: Different mechanisms of action
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    Chapter 25 Significance of calcium ions in the regulation of myocardial contractility
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    Chapter 26 Additive and non-additive positive inotropic effects in human and guinea-pig myocardium
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    Chapter 27 The cardiac Na+/H+ exchange system. Its role in inotropy
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    Chapter 28 Evidence for pharmacodynamic differences between cardiac glycosides of different polarities
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    Chapter 29 The positive inotropic action of mercury compounds on isolated heart muscle
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    Chapter 30 Chronic pretreatment with amrinone or milrinone induces no tachyphylaxis in mammalian cardiac muscle
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    Chapter 31 Left ventricular function after oral milrinone in patients with congestive heart failure. A hemodynamic and angiographic study
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    Chapter 32 The importance of skeletal muscles as a distribution volume for digitalis glycosides in guinea-pigs and human subjects
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    Chapter 33 Relevant metabolism of cardiac glycosides
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    Chapter 34 The dihydrogenation of digoxin
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    Chapter 35 Renal excretion and plasma levels of dihydrodigitoxin in volunteers and renally healthy and renally insufficient patients being treated with digitoxin
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    Chapter 36 Enzymatic basis for digitoxin metabolism and possible drug interactions in man
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    Chapter 37 Effect of quinidine on the inotropic effect of digoxin in isolated cat or guinea-pig papillary muscle
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    Chapter 38 Quinidine decreases the intestinal secretion of digoxin and digitoxin in the guinea-pig
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    Chapter 39 Quinidine-induced reduction of the biliary excretion of digoxin in patients
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    Chapter 40 Role of the bile acid transport system in hepatocellular ouabain uptake
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    Chapter 41 Distribution of digoxin, digitoxin and their cardioactive metabolites in human heart and kidney
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    Chapter 42 Application of HPLC-DAD instead of the guinea-pig test for the quantitative determination of cardiac glycosides
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    Chapter 43 Interaction between 16-acetyl-gitoxin and drugs
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    Chapter 44 Digitoxin protein binding in patients on hemodialysis
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    Chapter 45 The effect of physical exercise on the distribution and renal excretion of digoxin
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    Chapter 46 Ouabain binding to erythrocytes from neonates, blood cord and pregnant women
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    Chapter 47 Extracardiac effects of cardiac glycosides
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    Chapter 48 Effects of digitalis on renal tubular sodium reabsorption
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    Chapter 49 Ouabain-induced efflux of catecholamines and metabolites from blood vessels of normotensive and hypertensive dogs
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    Chapter 50 Digoxin-specific antibody treatment of digitalis toxicity: Update
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    Chapter 51 Kinetics of the Fab fragments of digoxin antibodies and of bound digoxin in patients with severe digoxin intoxication
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    Chapter 52 Influence of tubular Na-K-ATPase activity on the development of hyperkalemia in digoxin intoxications
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    Chapter 53 24-Hour Holter ECG in digoxin intoxicated patients
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    Chapter 54 Clinically relevant interactions with cardiac glycosides
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    Chapter 55 Importance of serum glycoside concentrations
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    Chapter 56 Metabolic aspects of compensatory mechanisms in cardiac failure
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    Chapter 57 Effects of digitalis glycosides on the systemic arterial and venous system: clinical importance in the pathophysiology of congestive heart failure
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    Chapter 58 Attenuation of cardiac glycoside effects during long-term treatment
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    Chapter 59 When to start digitalis?
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    Chapter 60 Cardiotonic effect of digitalis in sinus rhythm during exercise
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    Chapter 61 Digitalis treatment in pulmonary heart disease
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    Chapter 62 Cardiac glycosides for paroxysmal atrial fibrillation?
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    Chapter 63 Cardiac glycosides in anaesthesia
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    Chapter 64 Effects of preoperative digitalisation on postoperative left heart performance and incidence of complications following hip surgery. First results of a prospective study
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    Chapter 65 Digoxin therapy and mortality following confirmed or suspected myocardial infarction: Experience in the MILIS study
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    Chapter 66 Improvement of ventricular function by treatment with β-methyldigoxin in patients with sinus rhythm after extended myocardial infarction: An exercise-radionuclide-ventriculography study
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    Chapter 67 Effect of intravenous digoxin on left ventricular contractility at rest and during isometric exercise in intact and pharmacologically denervated heart
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    Chapter 68 Low versus medium dosage digoxin therapy in patients with heart failure. A randomized, double-blind, cross-over study
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    Chapter 69 The effects of digoxin and xamoterol in patients with moderate cardiac failure
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    Chapter 70 The clinical, haemodynamic, and pharmacological consequences of withdrawal of digoxin after long-term treatment in patients with heart failure in sinus rhythm
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    Chapter 71 New positive inotropic agents: Advantages and disadvantages
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    Chapter 72 When should digitalis be discontinued?
Overall attention for this book and its chapters
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Citations

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Title
Cardiac Glycosides 1785–1985
Published by
Steinkopff, January 1986
DOI 10.1007/978-3-662-11292-2
ISBNs
978-3-66-211294-6, 978-3-66-211292-2
Editors

Prof. Dr. Erland Erdmann, Prof. Dr. K. Greef, Prof. Dr. J. C. Skou

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Mendeley readers

The data shown below were compiled from readership statistics for 1 Mendeley reader of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 1 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 1 100%
Readers by discipline Count As %
Chemistry 1 100%

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