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Latency Locus Complements MicroRNA 155 Deficiency In Vivo

Overview of attention for article published in Journal of Virology, August 2013
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Title
Latency Locus Complements MicroRNA 155 Deficiency In Vivo
Published in
Journal of Virology, August 2013
DOI 10.1128/jvi.01620-13
Pubmed ID
Authors

Sang-Hoon Sin, Yong Baek Kim, Dirk P. Dittmer

Abstract

MicroRNA-155 (miR-155) is expressed in many cancers. It also executes evolutionary conserved functions in normal B cell development. We show that the Kaposi's sarcoma-associated herpesvirus (KSHV) latency locus, which contains an ortholog of miR-155, miR-K12-11, complements B cell deficiencies in miR-155 knockout mice. Germinal center (GC) formation was rescued in spleen, lymph node, and Peyer's patches. Immunoglobulin levels were restored. This demonstrates that KSHV can complement the normal, physiological function of miR-155.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 13 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Colombia 1 8%
Unknown 12 92%

Demographic breakdown

Readers by professional status Count As %
Researcher 4 31%
Student > Ph. D. Student 3 23%
Professor 2 15%
Professor > Associate Professor 2 15%
Student > Bachelor 1 8%
Other 0 0%
Unknown 1 8%
Readers by discipline Count As %
Agricultural and Biological Sciences 5 38%
Biochemistry, Genetics and Molecular Biology 3 23%
Immunology and Microbiology 2 15%
Veterinary Science and Veterinary Medicine 1 8%
Medicine and Dentistry 1 8%
Other 0 0%
Unknown 1 8%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 August 2013.
All research outputs
#20,655,488
of 25,371,288 outputs
Outputs from Journal of Virology
#23,559
of 25,689 outputs
Outputs of similar age
#159,374
of 210,368 outputs
Outputs of similar age from Journal of Virology
#153
of 193 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 25,689 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.5. This one is in the 3rd percentile – i.e., 3% of its peers scored the same or lower than it.
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