| Title |
Does Effective Depression Treatment Alone Reduce Secondary HIV Transmission Risk? Equivocal Findings from a Randomized Controlled Trial
|
|---|---|
| Published in |
AIDS and Behavior, August 2013
|
| DOI | 10.1007/s10461-013-0600-3 |
| Pubmed ID | |
| Authors |
Alexander C. Tsai, Matthew J. Mimiaga, James W. Dilley, Gwendolyn P. Hammer, Dan H. Karasic, Edwin D. Charlebois, James L. Sorensen, Steven A. Safren, David R. Bangsberg |
| Abstract |
Depressed mood has been associated with HIV transmission risk behavior. To determine whether effective depression treatment could reduce the frequency of sexual risk behavior, we analyzed secondary outcome data from a 36-week, two-arm, parallel-design, randomized controlled trial, in which homeless and marginally housed, HIV-infected persons with comorbid depressive disorders were randomized to receive either: (a) directly observed treatment with the antidepressant medication fluoxetine, or (b) referral to a local public mental health clinic. Self-reported sexual risk outcomes, which were measured at 3, 6, and 9 months, included: total number of sexual partners, unprotected sexual intercourse, unprotected sexual intercourse with an HIV-uninfected partner or a partner of unknown serostatus, and transactional sex. Estimates from generalized estimating equations regression models did not suggest consistent reductions in sexual risk behaviors resulting from treatment. Mental health interventions may need to combine depression treatment with specific skills training in order to achieve durable impacts on HIV prevention outcomes. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 112 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 112 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 17 | 15% |
| Student > Master | 16 | 14% |
| Researcher | 13 | 12% |
| Student > Doctoral Student | 12 | 11% |
| Student > Ph. D. Student | 11 | 10% |
| Other | 22 | 20% |
| Unknown | 21 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 23 | 21% |
| Medicine and Dentistry | 22 | 20% |
| Social Sciences | 15 | 13% |
| Nursing and Health Professions | 10 | 9% |
| Agricultural and Biological Sciences | 6 | 5% |
| Other | 10 | 9% |
| Unknown | 26 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 October 2013.
All research outputs
#18,572,005
of 23,849,058 outputs
Outputs from AIDS and Behavior
#2,846
of 3,566 outputs
Outputs of similar age
#145,361
of 201,734 outputs
Outputs of similar age from AIDS and Behavior
#56
of 66 outputs
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