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Toxicological Findings of Synthetic Cannabinoids in Recreational Users

Overview of attention for article published in Journal of Analytical Toxicology, August 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (90th percentile)
  • High Attention Score compared to outputs of the same age and source (84th percentile)

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1 blog
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10 X users
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1 Google+ user

Citations

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114 Dimensions

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99 Mendeley
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Title
Toxicological Findings of Synthetic Cannabinoids in Recreational Users
Published in
Journal of Analytical Toxicology, August 2013
DOI 10.1093/jat/bkt068
Pubmed ID
Authors

Robert Kronstrand, Markus Roman, Mikael Andersson, Arne Eklund

Abstract

In recent years, several synthetic cannabinoid compounds have become popular recreational drugs of abuse because of their psychoactive properties. This paper presents toxicological findings of synthetic cannabinoids in whole blood from some cases of severe intoxication including quantitative data from recreational users and a fatal intoxication. Samples were analyzed by liquid chromatography-tandem mass spectrometry in a scheduled multiple reaction mode after a basic liquid extraction. Twenty-nine synthetic cannabinoids were included in the method. In our data set of ~3000 cases, 28% were found positive for one or more synthetic cannabinoid(s). The most common finding was AM-2201. Most of the analytes had median concentrations of <0.5 ng/g in agreement with other published data. The emerging drugs MAM-2201 (n = 151) and UR-144 (n = 181) had mean (median) concentrations of 1.04 (0.37) and 1.26 (0.34), respectively. The toxicity of the synthetic cannabinoids seems to be worse than that of natural cannabis, probably owing to the higher potency and perhaps also to the presence of several different cannabinoids in the smoked incense and the difficulties of proper dosing. The acute toxic effects may under certain circumstances contribute to death.

X Demographics

X Demographics

The data shown below were collected from the profiles of 10 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 99 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 2%
Poland 1 1%
Unknown 96 97%

Demographic breakdown

Readers by professional status Count As %
Student > Master 15 15%
Researcher 13 13%
Student > Ph. D. Student 13 13%
Other 11 11%
Student > Bachelor 10 10%
Other 22 22%
Unknown 15 15%
Readers by discipline Count As %
Medicine and Dentistry 22 22%
Chemistry 12 12%
Pharmacology, Toxicology and Pharmaceutical Science 12 12%
Agricultural and Biological Sciences 8 8%
Neuroscience 6 6%
Other 17 17%
Unknown 22 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 16. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 November 2014.
All research outputs
#2,121,195
of 23,857,313 outputs
Outputs from Journal of Analytical Toxicology
#127
of 1,909 outputs
Outputs of similar age
#18,742
of 202,640 outputs
Outputs of similar age from Journal of Analytical Toxicology
#4
of 19 outputs
Altmetric has tracked 23,857,313 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,909 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.8. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 202,640 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 19 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 84% of its contemporaries.