Title |
Research opportunities in intraoperative radiation therapy: the next decade 2013–2023
|
---|---|
Published in |
Clinical and Translational Oncology, March 2013
|
DOI | 10.1007/s12094-013-1019-z |
Pubmed ID | |
Authors |
F. A. Calvo, C. V. Sole, M. E. González, E. D. Tangco, J. López-Tarjuelo, I. Koubychine, J. A. Santos, J. Pascau, R. Herranz, C. Ferrer |
Abstract |
The reality of intraoperative radiation therapy (IORT) practice is consistent with an efficient and highly precise radiation therapy technique to safely boost areas at risk for local recurrence. Long-term clinical experience has shown that IORT-containing multi-modality regimens appear to improve local disease control, if not survival in many diseases. Research with IORT is a multidisciplinary scenario that covers knowledge from radiation beam adapted development to advance molecular biology for bio-predictability of outcome. The technical parameters employed in IORT procedures are important information to be recorded for quality assurance and clinical results analysis. In addition, specific treatment planning systems for IORT procedures are available, to help in the treatment decision-making process. A systematic revision of opportunities for research and innovation in IORT is reported including radiation beam modulation, delivery, dosimetry and planning; infrastructure and treatment factors; experimental and clinical radiobiology; clinical trials, innovation and translational research development. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 2 | 20% |
United Kingdom | 2 | 20% |
New Zealand | 1 | 10% |
Australia | 1 | 10% |
Venezuela, Bolivarian Republic of | 1 | 10% |
Unknown | 3 | 30% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 8 | 80% |
Practitioners (doctors, other healthcare professionals) | 2 | 20% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 34 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Other | 6 | 18% |
Librarian | 5 | 15% |
Researcher | 5 | 15% |
Student > Ph. D. Student | 4 | 12% |
Student > Postgraduate | 3 | 9% |
Other | 8 | 24% |
Unknown | 3 | 9% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 11 | 32% |
Physics and Astronomy | 5 | 15% |
Engineering | 4 | 12% |
Business, Management and Accounting | 2 | 6% |
Biochemistry, Genetics and Molecular Biology | 2 | 6% |
Other | 4 | 12% |
Unknown | 6 | 18% |