| Title |
Population Pharmacokinetics of Tranexamic Acid in Paediatric Patients Undergoing Craniosynostosis Surgery
|
|---|---|
| Published in |
Clinical Pharmacokinetics, February 2013
|
| DOI | 10.1007/s40262-013-0033-1 |
| Pubmed ID | |
| Authors |
Susan M. Goobie, Petra M. Meier, Navil F. Sethna, Sulpicio G. Soriano, David Zurakowski, Snehal Samant, Luis M. Pereira |
| Abstract |
Tranexamic acid (TXA) effectively reduces blood loss and transfusion requirements during craniofacial surgery. The pharmacokinetics of TXA have not been fully characterized in paediatric patients and dosing regimens remain diverse in practice. A mixed-effects population analysis would characterize patient variability and guide dosing practices. |
Mendeley readers
The data shown below were compiled from readership statistics for 79 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 3% |
| Unknown | 77 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 14 | 18% |
| Student > Postgraduate | 9 | 11% |
| Student > Bachelor | 7 | 9% |
| Other | 7 | 9% |
| Student > Master | 7 | 9% |
| Other | 19 | 24% |
| Unknown | 16 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 33 | 42% |
| Chemistry | 7 | 9% |
| Agricultural and Biological Sciences | 4 | 5% |
| Biochemistry, Genetics and Molecular Biology | 2 | 3% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 3% |
| Other | 8 | 10% |
| Unknown | 23 | 29% |