| Title |
Theta Burst Stimulation of the Precuneus Modulates Resting State Connectivity in the Left Temporal Pole
|
|---|---|
| Published in |
Brain Topography, March 2017
|
| DOI | 10.1007/s10548-017-0559-x |
| Pubmed ID | |
| Authors |
Matteo Mancini, Chiara Mastropasqua, Sonia Bonnì, Viviana Ponzo, Mara Cercignani, Silvia Conforto, Giacomo Koch, Marco Bozzali |
| Abstract |
It has been shown that continuous theta burst stimulation (cTBS) over the precuneus acts on specific memory retrieval abilities. In order to study the neural mechanisms beyond these findings, we combined cTBS and resting-state functional magnetic resonance imaging. Our experimental protocol involved stimulation and sham conditions on a group of healthy subjects, and each condition included a baseline and two follow-up acquisitions (5 and 15 min after baseline) after cTBS. We analysed brain functional connectivity by means of graph theoretical measures, with a specific focus on the network modular structure. Our results showed that cTBS of the precuneus selectively affects the left temporal pole, decreasing its functional connectivity in the first follow-up. Moreover, we observed a significant increase in the size of the module of the precuneus in the second follow-up. Such effects were absent in the sham condition. We observed here a modulation of functional connectivity as a result of inhibitory stimulation over the precuneus. Such a modulation first acts indirectly on the temporal area and then extends the connectivity of the precuneus itself by a feed-back mechanism. Our current findings extend our previous behavioural observations and increase our understanding of the mechanisms underlying the stimulation of the precuneus. |
X Demographics
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Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 50% |
| Scientists | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 52 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 52 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 5 | 10% |
| Student > Bachelor | 5 | 10% |
| Researcher | 4 | 8% |
| Student > Master | 4 | 8% |
| Student > Doctoral Student | 3 | 6% |
| Other | 11 | 21% |
| Unknown | 20 | 38% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 13 | 25% |
| Psychology | 7 | 13% |
| Engineering | 2 | 4% |
| Medicine and Dentistry | 2 | 4% |
| Sports and Recreations | 1 | 2% |
| Other | 1 | 2% |
| Unknown | 26 | 50% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 April 2020.
All research outputs
#14,550,455
of 23,302,246 outputs
Outputs from Brain Topography
#266
of 488 outputs
Outputs of similar age
#174,648
of 308,744 outputs
Outputs of similar age from Brain Topography
#8
of 17 outputs
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