Title |
Endosymbiosis in trypanosomatids: the genomic cooperation between bacterium and host in the synthesis of essential amino acids is heavily influenced by multiple horizontal gene transfers
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Published in |
BMC Ecology and Evolution, September 2013
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DOI | 10.1186/1471-2148-13-190 |
Pubmed ID | |
Authors |
João MP Alves, Cecilia C Klein, Flávia Maia da Silva, André G Costa-Martins, Myrna G Serrano, Gregory A Buck, Ana Tereza R Vasconcelos, Marie-France Sagot, Marta MG Teixeira, Maria Cristina M Motta, Erney P Camargo |
Abstract |
Trypanosomatids of the genera Angomonas and Strigomonas live in a mutualistic association characterized by extensive metabolic cooperation with obligate endosymbiotic Betaproteobacteria. However, the role played by the symbiont has been more guessed by indirect means than evidenced. Symbiont-harboring trypanosomatids, in contrast to their counterparts lacking symbionts, exhibit lower nutritional requirements and are autotrophic for essential amino acids. To evidence the symbiont's contributions to this autotrophy, entire genomes of symbionts and trypanosomatids with and without symbionts were sequenced here. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Brazil | 2 | 2% |
United States | 2 | 2% |
Italy | 1 | <1% |
Germany | 1 | <1% |
United Kingdom | 1 | <1% |
Czechia | 1 | <1% |
Spain | 1 | <1% |
Mexico | 1 | <1% |
Unknown | 101 | 91% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 26 | 23% |
Researcher | 22 | 20% |
Student > Bachelor | 11 | 10% |
Student > Master | 9 | 8% |
Student > Doctoral Student | 8 | 7% |
Other | 18 | 16% |
Unknown | 17 | 15% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 54 | 49% |
Biochemistry, Genetics and Molecular Biology | 28 | 25% |
Immunology and Microbiology | 2 | 2% |
Earth and Planetary Sciences | 2 | 2% |
Philosophy | 1 | <1% |
Other | 3 | 3% |
Unknown | 21 | 19% |