| Title |
Brown adipose tissue thermogenesis in humans
|
|---|---|
| Published in |
Diabetologia, August 2013
|
| DOI | 10.1007/s00125-013-3005-y |
| Pubmed ID | |
| Authors |
P. Nuutila |
| Abstract |
The prevalence of obesity and type 2 diabetes is at epidemic proportions. Classical interventions aimed at targeting obesity, such as reducing energy intake or increasing exercise, are often not effective over the long term. In contrast to white adipocytes, which store energy, brown adipocytes generate heat via mitochondrial uncoupling protein 1, thereby acting as a defence against hypothermia and, potentially, obesity. In this issue of Diabetologia, Admiraal et al compare brown adipose tissue activation during cold exposure between two different ethnic groups: South Asians and Europids. The prevalence of abdominal obesity and type 2 diabetes differs among various ethnic groups and decreased BAT metabolic activity could be one causal factor. As yet, the clinical impact of this 'rediscovered' organ is largely unknown, but has potential as a drug target for obesity. |
Mendeley readers
The data shown below were compiled from readership statistics for 41 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 2% |
| Japan | 1 | 2% |
| Hungary | 1 | 2% |
| United States | 1 | 2% |
| Unknown | 37 | 90% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 9 | 22% |
| Researcher | 8 | 20% |
| Student > Bachelor | 7 | 17% |
| Student > Master | 5 | 12% |
| Other | 3 | 7% |
| Other | 6 | 15% |
| Unknown | 3 | 7% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 9 | 22% |
| Medicine and Dentistry | 9 | 22% |
| Biochemistry, Genetics and Molecular Biology | 7 | 17% |
| Neuroscience | 2 | 5% |
| Sports and Recreations | 2 | 5% |
| Other | 8 | 20% |
| Unknown | 4 | 10% |
Attention Score in Context
This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 December 2013.
All research outputs
#2,927,016
of 22,721,584 outputs
Outputs from Diabetologia
#1,427
of 5,031 outputs
Outputs of similar age
#26,343
of 197,410 outputs
Outputs of similar age from Diabetologia
#8
of 51 outputs
Altmetric has tracked 22,721,584 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 5,031 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 22.6. This one has gotten more attention than average, scoring higher than 71% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 197,410 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 51 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 82% of its contemporaries.