Title |
Neurogenic orthostatic hypotension: pathophysiology, evaluation, and management
|
---|---|
Published in |
Journal of Neurology, November 2012
|
DOI | 10.1007/s00415-012-6736-7 |
Pubmed ID | |
Authors |
Manuela Metzler, Susanne Duerr, Roberta Granata, Florian Krismer, David Robertson, Gregor K. Wenning |
Abstract |
Neurogenic orthostatic hypotension is a distinctive and treatable sign of cardiovascular autonomic dysfunction. It is caused by failure of noradrenergic neurotransmission that is associated with a range of primary or secondary autonomic disorders, including pure autonomic failure, Parkinson's disease with autonomic failure, multiple system atrophy as well as diabetic and nondiabetic autonomic neuropathies. Neurogenic orthostatic hypotension is commonly accompanied by autonomic dysregulation involving other organ systems such as the bowel and the bladder. In the present review, we provide an overview of the clinical presentation, pathophysiology, epidemiology, evaluation and management of neurogenic orthostatic hypotension focusing on neurodegenerative disorders. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 25% |
Unknown | 6 | 75% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 5 | 63% |
Scientists | 2 | 25% |
Practitioners (doctors, other healthcare professionals) | 1 | 13% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 3 | 2% |
Germany | 2 | 1% |
Korea, Republic of | 1 | <1% |
Austria | 1 | <1% |
India | 1 | <1% |
Brazil | 1 | <1% |
Russia | 1 | <1% |
United Kingdom | 1 | <1% |
Unknown | 154 | 93% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 28 | 17% |
Other | 19 | 12% |
Student > Master | 18 | 11% |
Student > Ph. D. Student | 16 | 10% |
Student > Bachelor | 14 | 8% |
Other | 35 | 21% |
Unknown | 35 | 21% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 75 | 45% |
Nursing and Health Professions | 14 | 8% |
Neuroscience | 13 | 8% |
Agricultural and Biological Sciences | 6 | 4% |
Biochemistry, Genetics and Molecular Biology | 6 | 4% |
Other | 15 | 9% |
Unknown | 36 | 22% |