Title |
Social Impairments in Chromosome 22q11.2 Deletion Syndrome (22q11.2DS): Autism Spectrum Disorder or a Different Endophenotype?
|
---|---|
Published in |
Journal of Autism and Developmental Disorders, September 2013
|
DOI | 10.1007/s10803-013-1920-x |
Pubmed ID | |
Authors |
Kathleen Angkustsiri, Beth Goodlin-Jones, Lesley Deprey, Khyati Brahmbhatt, Susan Harris, Tony J. Simon |
Abstract |
High prevalence of autism spectrum disorders (ASD) has been reported in 22q11.2DS, although this has been based solely on parent report measures. This study describes the presence of ASD using a procedure more similar to that used in clinical practice by incorporating history (Social Communication Questionnaire) AND a standardized observation measure (Autism Diagnostic Observation Schedule) and suggests that ASD is not as common as previously reported in 22q11.2DS. Differences in methodology, along with comorbid conditions such as anxiety, likely contribute to false elevations in ASD prevalence and information from multiple sources should be included in the evaluation of ASD. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 5 | 23% |
Australia | 2 | 9% |
Canada | 2 | 9% |
Ireland | 1 | 5% |
Spain | 1 | 5% |
France | 1 | 5% |
United Kingdom | 1 | 5% |
Unknown | 9 | 41% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 18 | 82% |
Scientists | 3 | 14% |
Practitioners (doctors, other healthcare professionals) | 1 | 5% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | <1% |
United States | 1 | <1% |
Portugal | 1 | <1% |
Unknown | 146 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 31 | 21% |
Student > Master | 31 | 21% |
Researcher | 19 | 13% |
Student > Bachelor | 13 | 9% |
Student > Doctoral Student | 9 | 6% |
Other | 22 | 15% |
Unknown | 24 | 16% |
Readers by discipline | Count | As % |
---|---|---|
Psychology | 39 | 26% |
Medicine and Dentistry | 35 | 23% |
Agricultural and Biological Sciences | 13 | 9% |
Neuroscience | 9 | 6% |
Nursing and Health Professions | 6 | 4% |
Other | 17 | 11% |
Unknown | 30 | 20% |