| Title |
Drug-resistant tuberculosis in two children in Greece: Report of the first extensively drug-resistant case
|
|---|---|
| Published in |
European Journal of Pediatrics, August 2012
|
| DOI | 10.1007/s00431-012-1811-8 |
| Pubmed ID | |
| Authors |
Aspasia Katragkou, Charalampos Antachopoulos, Elpis Hatziagorou, Maria Sdougka, Emmanuel Roilides, John Tsanakas |
| Abstract |
Extensively drug-resistant (XDR) tuberculosis (TB) represents a serious and growing problem in both endemic and non-endemic countries. We describe a 2.5-year-old girl with XDR-pulmonary TB and an 18-month-old boy with pre-XDR-central nervous system TB. Patients received individualized treatment with second-line anti-TB agents based on genotypic and phenotypic drug susceptibility testing results. Both children achieved culture conversion 3 months and 1 month after treatment initiation, respectively. The child with XDR-pulmonary TB showed evidence of cure while treatment adverse events were managed without treatment interruption. The child with pre-XDR-central nervous system TB after 6-month hospitalization with multiple infectious complications had a dismal end due to hepatic insufficiency possibly related to anti-TB treatment. This is the first report of children with pre-XDR and XDR TB in Greece, emphasizing the public health dimensions and management complexity of XDR TB. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 52 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Malaysia | 1 | 2% |
| Greece | 1 | 2% |
| Unknown | 50 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 9 | 17% |
| Student > Bachelor | 7 | 13% |
| Student > Master | 6 | 12% |
| Student > Doctoral Student | 4 | 8% |
| Student > Ph. D. Student | 4 | 8% |
| Other | 10 | 19% |
| Unknown | 12 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 23 | 44% |
| Nursing and Health Professions | 5 | 10% |
| Agricultural and Biological Sciences | 3 | 6% |
| Social Sciences | 2 | 4% |
| Immunology and Microbiology | 2 | 4% |
| Other | 3 | 6% |
| Unknown | 14 | 27% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 September 2013.
All research outputs
#18,347,414
of 22,721,584 outputs
Outputs from European Journal of Pediatrics
#3,096
of 3,676 outputs
Outputs of similar age
#129,676
of 169,232 outputs
Outputs of similar age from European Journal of Pediatrics
#16
of 30 outputs
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