| Title |
Sox9 Is Upstream of MicroRNA-140 in Cartilage
|
|---|---|
| Published in |
Applied Biochemistry and Biotechnology, November 2011
|
| DOI | 10.1007/s12010-011-9404-y |
| Pubmed ID | |
| Authors |
Yukio Nakamura, Xinjun He, Hiroyuki Kato, Shigeyuki Wakitani, Tatsuya Kobayashi, Sumiko Watanabe, Atsumi Iida, Hideaki Tahara, Matthew L. Warman, Ramida Watanapokasin, John H. Postlethwait |
| Abstract |
MicroRNA-140 (miR-140) is specifically expressed in developing cartilage tissues. We have previously reported that miR-140 plays an important role during palatal cartilage development by modulating platelet-derived growth factor receptor alpha (pdgfra) in zebrafish. However, the regulatory mechanism of miR-140 in cartilage is still unknown. Using developing zebrafish, sox9a mutant (sox9a-/-) and sox9b mutant (sox9b-/-) zebrafish and SOX9 small interfering RNA in human chondrocytes, T/C-28 cells, we found that miR-140 is regulated by the cartilage master transcription regulator Sox9 in zebrafish and mammalian cells. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 50% |
| Members of the public | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 58 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 1 | 2% |
| India | 1 | 2% |
| United States | 1 | 2% |
| Norway | 1 | 2% |
| Unknown | 54 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 10 | 17% |
| Researcher | 10 | 17% |
| Student > Master | 7 | 12% |
| Professor > Associate Professor | 6 | 10% |
| Student > Doctoral Student | 3 | 5% |
| Other | 9 | 16% |
| Unknown | 13 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 14 | 24% |
| Biochemistry, Genetics and Molecular Biology | 12 | 21% |
| Medicine and Dentistry | 9 | 16% |
| Immunology and Microbiology | 2 | 3% |
| Neuroscience | 2 | 3% |
| Other | 5 | 9% |
| Unknown | 14 | 24% |
Attention Score in Context
This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 January 2017.
All research outputs
#4,431,795
of 22,721,584 outputs
Outputs from Applied Biochemistry and Biotechnology
#182
of 2,496 outputs
Outputs of similar age
#26,137
of 141,700 outputs
Outputs of similar age from Applied Biochemistry and Biotechnology
#5
of 27 outputs
Altmetric has tracked 22,721,584 research outputs across all sources so far. Compared to these this one has done well and is in the 80th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,496 research outputs from this source. They receive a mean Attention Score of 3.2. This one has done particularly well, scoring higher than 92% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 141,700 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 81% of its contemporaries.
We're also able to compare this research output to 27 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 81% of its contemporaries.