| Title |
Abnormal Transient Pupillary Light Reflex in Individuals with Autism Spectrum Disorders
|
|---|---|
| Published in |
Journal of Autism and Developmental Disorders, June 2009
|
| DOI | 10.1007/s10803-009-0767-7 |
| Pubmed ID | |
| Authors |
Xiaofei Fan, Judith H. Miles, Nicole Takahashi, Gang Yao |
| Abstract |
Computerized binocular infrared pupillography was used to measure the transient pupillary light reflex (PLR) in both children with autism spectrum disorders (ASDs) and children with typical development. We found that participants with ASDs showed significantly longer PLR latency, smaller constriction amplitude and lower constriction velocity than children with typical development. The PLR latency alone can be used to discriminate the ASD group from the control group with a cross-validated success rate of 89.6%. By adding the constriction amplitude, the percentage of correct classification can be further improved to 92.5%. In addition, the right-lateralization of contraction anisocoria that was observed in participants with typical development was not observed in those with ASDs. Further studies are necessary to understand the origin and implications of these observations. It is anticipated that as potential biomarkers, these pupillary light reflex measurements will advance our understanding of neurodevelopmental differences in the autism brain. |
X Demographics
The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 40% |
| Unknown | 3 | 60% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 5 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 150 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 1% |
| United Kingdom | 1 | <1% |
| Canada | 1 | <1% |
| Unknown | 146 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 28 | 19% |
| Researcher | 21 | 14% |
| Student > Master | 17 | 11% |
| Student > Doctoral Student | 16 | 11% |
| Student > Bachelor | 11 | 7% |
| Other | 26 | 17% |
| Unknown | 31 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 34 | 23% |
| Neuroscience | 22 | 15% |
| Engineering | 15 | 10% |
| Agricultural and Biological Sciences | 13 | 9% |
| Medicine and Dentistry | 13 | 9% |
| Other | 16 | 11% |
| Unknown | 37 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 14. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 December 2023.
All research outputs
#2,545,264
of 25,081,505 outputs
Outputs from Journal of Autism and Developmental Disorders
#1,116
of 5,419 outputs
Outputs of similar age
#8,976
of 120,396 outputs
Outputs of similar age from Journal of Autism and Developmental Disorders
#5
of 35 outputs
Altmetric has tracked 25,081,505 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 5,419 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.2. This one has done well, scoring higher than 79% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 120,396 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 35 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 88% of its contemporaries.