| Title |
When you can’t trust the DNA: RNA editing changes transcript sequences
|
|---|---|
| Published in |
Cellular and Molecular Life Sciences, October 2010
|
| DOI | 10.1007/s00018-010-0538-9 |
| Pubmed ID | |
| Authors |
Volker Knoop |
| Abstract |
RNA editing describes targeted sequence alterations in RNAs so that the transcript sequences differ from their DNA template. Since the original discovery of RNA editing in trypanosomes nearly 25 years ago more than a dozen such processes of nucleotide insertions, deletions, and exchanges have been identified in evolutionarily widely separated groups of the living world including plants, animals, fungi, protists, bacteria, and viruses. In many cases gene expression in mitochondria is affected, but RNA editing also takes place in chloroplasts and in nucleocytosolic genetic environments. While some RNA editing systems largely seem to repair defect genes (cryptogenes), others have obvious functions in modulating gene activities. The present review aims for an overview on the current states of research in the different systems of RNA editing by following a historic timeline along the respective original discoveries. |
Mendeley readers
The data shown below were compiled from readership statistics for 169 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Netherlands | 2 | 1% |
| United Kingdom | 2 | 1% |
| United States | 2 | 1% |
| Ireland | 1 | <1% |
| Canada | 1 | <1% |
| Portugal | 1 | <1% |
| Unknown | 160 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 45 | 27% |
| Researcher | 42 | 25% |
| Student > Master | 15 | 9% |
| Student > Bachelor | 11 | 7% |
| Professor > Associate Professor | 10 | 6% |
| Other | 22 | 13% |
| Unknown | 24 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 82 | 49% |
| Biochemistry, Genetics and Molecular Biology | 38 | 22% |
| Medicine and Dentistry | 3 | 2% |
| Immunology and Microbiology | 2 | 1% |
| Earth and Planetary Sciences | 2 | 1% |
| Other | 13 | 8% |
| Unknown | 29 | 17% |
Attention Score in Context
This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 August 2013.
All research outputs
#3,814,081
of 24,129,125 outputs
Outputs from Cellular and Molecular Life Sciences
#639
of 5,569 outputs
Outputs of similar age
#14,158
of 102,220 outputs
Outputs of similar age from Cellular and Molecular Life Sciences
#2
of 25 outputs
Altmetric has tracked 24,129,125 research outputs across all sources so far. Compared to these this one has done well and is in the 84th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 5,569 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one has done well, scoring higher than 85% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 102,220 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 83% of its contemporaries.
We're also able to compare this research output to 25 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.