Title |
Does a 10-valent pneumococcal-Haemophilus influenzae protein D conjugate vaccine prevent respiratory exacerbations in children with recurrent protracted bacterial bronchitis, chronic suppurative lung disease and bronchiectasis: protocol for a randomised controlled trial
|
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Published in |
Trials, September 2013
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DOI | 10.1186/1745-6215-14-282 |
Pubmed ID | |
Authors |
Kerry-Ann F O’Grady, Keith Grimwood, Allan Cripps, Edward K Mulholland, Peter Morris, Paul J Torzillo, Nicholas Wood, Heidi Smith-Vaughan, Amber Revell, Andrew Wilson, Peter Van Asperen, Peter Richmond, Ruth Thornton, Sheree Rablin, Anne B Chang |
Abstract |
Recurrent protracted bacterial bronchitis (PBB), chronic suppurative lung disease (CSLD) and bronchiectasis are characterised by a chronic wet cough and are important causes of childhood respiratory morbidity globally. Haemophilus influenzae and Streptococcus pneumoniae are the most commonly associated pathogens. As respiratory exacerbations impair quality of life and may be associated with disease progression, we will determine if the novel 10-valent pneumococcal-Haemophilus influenzae protein D conjugate vaccine (PHiD-CV) reduces exacerbations in these children. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Australia | 1 | 50% |
United Kingdom | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 50% |
Scientists | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 120 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 20 | 17% |
Student > Ph. D. Student | 13 | 11% |
Researcher | 13 | 11% |
Student > Master | 13 | 11% |
Other | 6 | 5% |
Other | 27 | 23% |
Unknown | 28 | 23% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 45 | 38% |
Nursing and Health Professions | 14 | 12% |
Psychology | 8 | 7% |
Biochemistry, Genetics and Molecular Biology | 6 | 5% |
Agricultural and Biological Sciences | 3 | 3% |
Other | 12 | 10% |
Unknown | 32 | 27% |