| Title |
Neuroprotective mechanisms of astaxanthin: a potential therapeutic role in preserving cognitive function in age and neurodegeneration
|
|---|---|
| Published in |
GeroScience, February 2017
|
| DOI | 10.1007/s11357-017-9958-x |
| Pubmed ID | |
| Authors |
Bethany Grimmig, Seol-Hee Kim, Kevin Nash, Paula C. Bickford, R. Douglas Shytle |
| Abstract |
Astaxanthin (AXT) is a carotenoid with multiple health benefits. It is currently marketed as a health supplement and is well known for its antioxidant capacity. Recent evidence has emerged to suggest a broad range of biological activities. The interest in this compound has increased dramatically over the last few years and many studies are now applying this molecule across many disease models. Results from the current research are beginning to come together to suggest neuroprotective properties including anti-inflammatory, anti-apoptotic, and antioxidant effects, as well as the potential to promote or maintain neural plasticity. These emergent mechanisms of actions implicate AXT as a promising therapeutic agent for neurodegenerative disease. This review will examine and extrapolate from the recent literature to build support for the use of AXT in mitigating neuropathy in normal aging and neurodegenerative disease. |
X Demographics
The data shown below were collected from the profiles of 10 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 20% |
| Canada | 1 | 10% |
| India | 1 | 10% |
| Georgia | 1 | 10% |
| Spain | 1 | 10% |
| Unknown | 4 | 40% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 6 | 60% |
| Practitioners (doctors, other healthcare professionals) | 2 | 20% |
| Scientists | 2 | 20% |
Mendeley readers
The data shown below were compiled from readership statistics for 189 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 189 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 29 | 15% |
| Student > Master | 27 | 14% |
| Student > Bachelor | 21 | 11% |
| Student > Ph. D. Student | 19 | 10% |
| Other | 10 | 5% |
| Other | 32 | 17% |
| Unknown | 51 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 34 | 18% |
| Biochemistry, Genetics and Molecular Biology | 23 | 12% |
| Medicine and Dentistry | 21 | 11% |
| Pharmacology, Toxicology and Pharmaceutical Science | 15 | 8% |
| Neuroscience | 13 | 7% |
| Other | 30 | 16% |
| Unknown | 53 | 28% |
Attention Score in Context
This research output has an Altmetric Attention Score of 22. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 March 2024.
All research outputs
#1,724,176
of 25,362,520 outputs
Outputs from GeroScience
#199
of 1,587 outputs
Outputs of similar age
#36,735
of 439,255 outputs
Outputs of similar age from GeroScience
#3
of 14 outputs
Altmetric has tracked 25,362,520 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,587 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 17.0. This one has done well, scoring higher than 87% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 439,255 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 91% of its contemporaries.
We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 85% of its contemporaries.