Title |
A Single Dose of Azithromycin Does Not Improve Clinical Outcomes of Children Hospitalised with Bronchiolitis: A Randomised, Placebo-Controlled Trial
|
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Published in |
PLOS ONE, September 2013
|
DOI | 10.1371/journal.pone.0074316 |
Pubmed ID | |
Authors |
Gabrielle B. McCallum, Peter S. Morris, Mark D. Chatfield, Carolyn Maclennan, Andrew V. White, Theo P. Sloots, Ian M. Mackay, Anne B. Chang |
Abstract |
Bronchiolitis, one of the most common reasons for hospitalisation in young children, is particularly problematic in Indigenous children. Macrolides may be beneficial in settings where children have high rates of nasopharyngeal bacterial carriage and frequent prolonged illness. The aim of our double-blind placebo-controlled randomised trial was to determine if a large single dose of azithromycin (compared to placebo) reduced length of stay (LOS), duration of oxygen (O2) and respiratory readmissions within 6 months of children hospitalised with bronchiolitis. We also determined the effect of azithromycin on nasopharyngeal microbiology. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 79 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 12 | 15% |
Student > Doctoral Student | 10 | 13% |
Researcher | 9 | 11% |
Student > Bachelor | 7 | 9% |
Other | 5 | 6% |
Other | 16 | 20% |
Unknown | 20 | 25% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 38 | 48% |
Nursing and Health Professions | 5 | 6% |
Biochemistry, Genetics and Molecular Biology | 4 | 5% |
Pharmacology, Toxicology and Pharmaceutical Science | 3 | 4% |
Agricultural and Biological Sciences | 2 | 3% |
Other | 6 | 8% |
Unknown | 21 | 27% |