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A Single Dose of Azithromycin Does Not Improve Clinical Outcomes of Children Hospitalised with Bronchiolitis: A Randomised, Placebo-Controlled Trial

Overview of attention for article published in PLOS ONE, September 2013
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Title
A Single Dose of Azithromycin Does Not Improve Clinical Outcomes of Children Hospitalised with Bronchiolitis: A Randomised, Placebo-Controlled Trial
Published in
PLOS ONE, September 2013
DOI 10.1371/journal.pone.0074316
Pubmed ID
Authors

Gabrielle B. McCallum, Peter S. Morris, Mark D. Chatfield, Carolyn Maclennan, Andrew V. White, Theo P. Sloots, Ian M. Mackay, Anne B. Chang

Abstract

Bronchiolitis, one of the most common reasons for hospitalisation in young children, is particularly problematic in Indigenous children. Macrolides may be beneficial in settings where children have high rates of nasopharyngeal bacterial carriage and frequent prolonged illness. The aim of our double-blind placebo-controlled randomised trial was to determine if a large single dose of azithromycin (compared to placebo) reduced length of stay (LOS), duration of oxygen (O2) and respiratory readmissions within 6 months of children hospitalised with bronchiolitis. We also determined the effect of azithromycin on nasopharyngeal microbiology.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 79 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 79 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 12 15%
Student > Doctoral Student 10 13%
Researcher 9 11%
Student > Bachelor 7 9%
Other 5 6%
Other 16 20%
Unknown 20 25%
Readers by discipline Count As %
Medicine and Dentistry 38 48%
Nursing and Health Professions 5 6%
Biochemistry, Genetics and Molecular Biology 4 5%
Pharmacology, Toxicology and Pharmaceutical Science 3 4%
Agricultural and Biological Sciences 2 3%
Other 6 8%
Unknown 21 27%