| Title |
Molecular mechanisms regulating NETosis in infection and disease
|
|---|---|
| Published in |
Seminars in Immunopathology, June 2013
|
| DOI | 10.1007/s00281-013-0384-6 |
| Pubmed ID | |
| Authors |
Nora Branzk, Venizelos Papayannopoulos |
| Abstract |
Neutrophils are the foot soldiers of the immune system. They home in to the site of infection and kill pathogens by phagocytosis, degranulation, and the release of web-like structures called neutrophil extracellular traps (NETs) that trap and kill a variety of microbes. NETs have been shown to play a multitude of additional roles in immunity but have also been implicated in inflammatory and autoimmune disease. Here, we discuss the role of NETs in these various contexts with a particular emphasis on the molecular mechanisms that regulate NET release and clearance. We highlight the comprehensive concepts and explore the important open questions in the field. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Saudi Arabia | 2 | 67% |
| Spain | 1 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 479 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Netherlands | 2 | <1% |
| United States | 2 | <1% |
| Germany | 1 | <1% |
| Austria | 1 | <1% |
| Russia | 1 | <1% |
| Canada | 1 | <1% |
| Greece | 1 | <1% |
| Poland | 1 | <1% |
| Unknown | 469 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 103 | 22% |
| Student > Bachelor | 63 | 13% |
| Researcher | 61 | 13% |
| Student > Master | 60 | 13% |
| Student > Doctoral Student | 35 | 7% |
| Other | 74 | 15% |
| Unknown | 83 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 119 | 25% |
| Medicine and Dentistry | 83 | 17% |
| Biochemistry, Genetics and Molecular Biology | 67 | 14% |
| Immunology and Microbiology | 61 | 13% |
| Pharmacology, Toxicology and Pharmaceutical Science | 16 | 3% |
| Other | 37 | 8% |
| Unknown | 96 | 20% |
Attention Score in Context
This research output has an Altmetric Attention Score of 76. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 May 2022.
All research outputs
#531,406
of 24,475,473 outputs
Outputs from Seminars in Immunopathology
#11
of 563 outputs
Outputs of similar age
#3,678
of 201,623 outputs
Outputs of similar age from Seminars in Immunopathology
#1
of 5 outputs
Altmetric has tracked 24,475,473 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 563 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.2. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 201,623 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them