| Title |
High prevalence of subclinical atherosclerosis in Brazilian postmenopausal women with low and intermediate risk by Framingham score
|
|---|---|
| Published in |
The International Journal of Cardiovascular Imaging, October 2016
|
| DOI | 10.1007/s10554-016-1002-1 |
| Pubmed ID | |
| Authors |
Ana Claudia Gomes Pereira Petisco, Jorge Eduardo Assef, Carlos Alberto de Jesus, Mohamed Hassan Saleh, Jose Eduardo Martins Barbosa, David Costa de Souza Le Bihan, Ibraim Masciarelli França Pinto, Simone Rolim Fernandes Fontes Pedra, Rodrigo Bellio de Mattos Barretto, Amanda Guerra de Moraes Rego Sousa |
| Abstract |
Cardiovascular diseases are the leading cause of mortality among women in several countries. Early detection of subclinical atherosclerosis (SA) could enable the adoption of preventive measures to avoid cardiovascular events. This study aimed to determine the prevalence of SA in Brazilian asymptomatic postmenopausal women in Framingham Risk Score (FRS) low and intermediate groups. Computed tomography (CT) and ultrasound (US) scans were performed in 138 asymptomatic postmenopausal women (56.1 ± 4.9 years of age) to survey for coronary artery and aortic calcification (CT scan) and assess carotid intima-media thickness (CIMT) and identify carotid plaques (US). The mean FRS was 2.64 ± 2.13 %. The prevalence of increased CIMT, carotid plaques, increased CIMT and/or plaques, coronary artery calcification (CAC) >0 and aortic calcification (AC) were, respectively, 45.7, 37.7, 62.3, 23.9 and 45.7 %. Normal imaging tests were found in 22.4 %. SA, defined as at least one abnormal imaging test, was associated with age, FRS, waist-to-rip ratio, systolic and diastolic blood pressure, HDL-c and ApoA1 levels, and ApoA1/ApoB ratio. In logistic regression, SA was associated with higher age (OR 1.108, 95 % CI 1.010-1.215, p = 0.029) and lower ApoA1 levels (OR 0.979, 95 % CI 0.960-0.998, p = 0.029). SA was prevalent in Brazilian postmenopausal women with low and intermediate risk groups (FRS) and was associated with higher age and lower levels of ApoA1. Carotid atherosclerosis was the most common presentation of SA in this group. |
Mendeley readers
The data shown below were compiled from readership statistics for 41 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 41 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Doctoral Student | 9 | 22% |
| Student > Master | 8 | 20% |
| Student > Bachelor | 4 | 10% |
| Student > Ph. D. Student | 4 | 10% |
| Researcher | 2 | 5% |
| Other | 3 | 7% |
| Unknown | 11 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 12 | 29% |
| Nursing and Health Professions | 4 | 10% |
| Psychology | 2 | 5% |
| Environmental Science | 1 | 2% |
| Unspecified | 1 | 2% |
| Other | 7 | 17% |
| Unknown | 14 | 34% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 March 2017.
All research outputs
#20,655,488
of 25,371,288 outputs
Outputs from The International Journal of Cardiovascular Imaging
#1,292
of 2,012 outputs
Outputs of similar age
#248,989
of 322,956 outputs
Outputs of similar age from The International Journal of Cardiovascular Imaging
#17
of 37 outputs
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