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Population Pharmacokinetics of Tacrolimus in Adult Kidney Transplant Patients

Overview of attention for article published in Therapeutic Drug Monitoring, February 2014
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Title
Population Pharmacokinetics of Tacrolimus in Adult Kidney Transplant Patients
Published in
Therapeutic Drug Monitoring, February 2014
DOI 10.1097/ftd.0b013e31829f1ab8
Pubmed ID
Authors

Troels K. Bergmann, Stefanie Hennig, Katherine A. Barraclough, Nicole M. Isbel, Christine E. Staatz

Abstract

The aims of this study were to develop a population pharmacokinetic model of tacrolimus in adult kidney transplant recipients, to use this model to compare cytochrome P450 3A5 (CYP3A5) genotype-based initial dosing of tacrolimus with standard per-kilogram-based dosing, and to predict the best starting dose of tacrolimus based on patient genotype to achieve a trough concentration between 6 and 10 µg/L by day 5 posttransplantation.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 50 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 2%
Unknown 49 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 10 20%
Student > Master 9 18%
Student > Doctoral Student 8 16%
Researcher 7 14%
Student > Bachelor 5 10%
Other 7 14%
Unknown 4 8%
Readers by discipline Count As %
Medicine and Dentistry 23 46%
Pharmacology, Toxicology and Pharmaceutical Science 11 22%
Agricultural and Biological Sciences 3 6%
Computer Science 2 4%
Unspecified 1 2%
Other 3 6%
Unknown 7 14%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 January 2014.
All research outputs
#17,283,763
of 25,371,288 outputs
Outputs from Therapeutic Drug Monitoring
#1,107
of 1,787 outputs
Outputs of similar age
#203,527
of 322,717 outputs
Outputs of similar age from Therapeutic Drug Monitoring
#9
of 20 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,787 research outputs from this source. They receive a mean Attention Score of 4.0. This one is in the 26th percentile – i.e., 26% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 322,717 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 20 others from the same source and published within six weeks on either side of this one. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.