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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Genome-wide association study of endometrial cancer in E2C2
|
|---|---|
| Published in |
Human Genetics, October 2013
|
| DOI | 10.1007/s00439-013-1369-1 |
| Pubmed ID | |
| Authors |
Immaculata De Vivo, Jennifer Prescott, Veronica Wendy Setiawan, Sara H. Olson, Nicolas Wentzensen, The Australian National Endometrial Cancer Study Group, John Attia, Amanda Black, Louise Brinton, Chu Chen, Constance Chen, Linda S. Cook, Marta Crous-Bou, Jennifer Doherty, Alison M. Dunning, Douglas F. Easton, Christine M. Friedenreich, Montserrat Garcia-Closas, Mia M. Gaudet, Christopher Haiman, Susan E. Hankinson, Patricia Hartge, Brian E. Henderson, Elizabeth Holliday, Pamela L. Horn-Ross, David J. Hunter, Loic Le Marchand, Xiaolin Liang, Jolanta Lissowska, Jirong Long, Lingeng Lu, Anthony M. Magliocco, Mark McEvoy, Tracy A. O’Mara, Irene Orlow, Jodie N. Painter, Loreall Pooler, Radhai Rastogi, Timothy R. Rebbeck, Harvey Risch, Carlotta Sacerdote, Fredrick Schumacher, Rodney J. Scott, Xin Sheng, Xiao-ou Shu, Amanda B. Spurdle, Deborah Thompson, David VanDen Berg, Noel S. Weiss, Lucy Xia, Yong-Bing Xiang, Hannah P. Yang, Herbert Yu, Wei Zheng, Stephen Chanock, Peter Kraft |
| Abstract |
Endometrial cancer (EC), a neoplasm of the uterine epithelial lining, is the most common gynecological malignancy in developed countries and the fourth most common cancer among US women. Women with a family history of EC have an increased risk for the disease, suggesting that inherited genetic factors play a role. We conducted a two-stage genome-wide association study of Type I EC. Stage 1 included 5,472 women (2,695 cases and 2,777 controls) of European ancestry from seven studies. We selected independent single-nucleotide polymorphisms (SNPs) that displayed the most significant associations with EC in Stage 1 for replication among 17,948 women (4,382 cases and 13,566 controls) in a multiethnic population (African America, Asian, Latina, Hawaiian and European ancestry), from nine studies. Although no novel variants reached genome-wide significance, we replicated previously identified associations with genetic markers near the HNF1B locus. Our findings suggest that larger studies with specific tumor classification are necessary to identify novel genetic polymorphisms associated with EC susceptibility. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 44 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Belgium | 1 | 2% |
| Unknown | 43 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 15 | 34% |
| Student > Ph. D. Student | 10 | 23% |
| Student > Bachelor | 3 | 7% |
| Other | 2 | 5% |
| Student > Postgraduate | 2 | 5% |
| Other | 4 | 9% |
| Unknown | 8 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 11 | 25% |
| Agricultural and Biological Sciences | 7 | 16% |
| Medicine and Dentistry | 7 | 16% |
| Neuroscience | 3 | 7% |
| Social Sciences | 1 | 2% |
| Other | 1 | 2% |
| Unknown | 14 | 32% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 October 2013.
All research outputs
#15,281,593
of 22,725,280 outputs
Outputs from Human Genetics
#2,533
of 2,950 outputs
Outputs of similar age
#128,388
of 208,527 outputs
Outputs of similar age from Human Genetics
#19
of 27 outputs
Altmetric has tracked 22,725,280 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,950 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.2. This one is in the 10th percentile – i.e., 10% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 208,527 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 27 others from the same source and published within six weeks on either side of this one. This one is in the 18th percentile – i.e., 18% of its contemporaries scored the same or lower than it.