| Title |
Evolution of Spliceosomal snRNA Genes in Metazoan Animals
|
|---|---|
| Published in |
Journal of Molecular Evolution, November 2008
|
| DOI | 10.1007/s00239-008-9149-6 |
| Pubmed ID | |
| Authors |
Manuela Marz, Toralf Kirsten, Peter F. Stadler |
| Abstract |
While studies of the evolutionary histories of protein families are commonplace, little is known on noncoding RNAs beyond microRNAs and some snoRNAs. Here we investigate in detail the evolutionary history of the nine spliceosomal snRNA families (U1, U2, U4, U5, U6, U11, U12, U4atac, and U6atac) across the completely or partially sequenced genomes of metazoan animals. Representatives of the five major spliceosomal snRNAs were found in all genomes. None of the minor splicesomal snRNAs were detected in nematodes or in the shotgun traces of Oikopleura dioica, while in all other animal genomes at most one of them is missing. Although snRNAs are present in multiple copies in most genomes, distinguishable paralogue groups are not stable over long evolutionary times, although they appear independently in several clades. In general, animal snRNA secondary structures are highly conserved, albeit, in particular, U11 and U12 in insects exhibit dramatic variations. An analysis of genomic context of snRNAs reveals that they behave like mobile elements, exhibiting very little syntenic conservation. |
Mendeley readers
The data shown below were compiled from readership statistics for 76 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Colombia | 1 | 1% |
| Germany | 1 | 1% |
| Norway | 1 | 1% |
| Austria | 1 | 1% |
| Brazil | 1 | 1% |
| Taiwan | 1 | 1% |
| United States | 1 | 1% |
| Poland | 1 | 1% |
| Unknown | 68 | 89% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 22 | 29% |
| Student > Ph. D. Student | 18 | 24% |
| Student > Bachelor | 12 | 16% |
| Professor > Associate Professor | 4 | 5% |
| Student > Master | 4 | 5% |
| Other | 10 | 13% |
| Unknown | 6 | 8% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 42 | 55% |
| Biochemistry, Genetics and Molecular Biology | 23 | 30% |
| Veterinary Science and Veterinary Medicine | 1 | 1% |
| Computer Science | 1 | 1% |
| Immunology and Microbiology | 1 | 1% |
| Other | 1 | 1% |
| Unknown | 7 | 9% |
Attention Score in Context
This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 December 2020.
All research outputs
#3,645,315
of 22,725,280 outputs
Outputs from Journal of Molecular Evolution
#179
of 1,435 outputs
Outputs of similar age
#20,023
of 166,244 outputs
Outputs of similar age from Journal of Molecular Evolution
#3
of 10 outputs
Altmetric has tracked 22,725,280 research outputs across all sources so far. Compared to these this one has done well and is in the 83rd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,435 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.2. This one has done well, scoring higher than 87% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 166,244 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than 7 of them.