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Noncerebral Amyloidoses: Aspects on Seeding, Cross-Seeding, and Transmission

Overview of attention for article published in Cold Spring Harbor Perspectives in Medicine, January 2017
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Mentioned by

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4 Wikipedia pages

Citations

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26 Dimensions

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38 Mendeley
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Title
Noncerebral Amyloidoses: Aspects on Seeding, Cross-Seeding, and Transmission
Published in
Cold Spring Harbor Perspectives in Medicine, January 2017
DOI 10.1101/cshperspect.a024323
Pubmed ID
Authors

Gunilla T. Westermark, Marcus Fändrich, Katarzyna Lundmark, Per Westermark

Abstract

More than 30 proteins form amyloid in humans, most of them outside of the brain. Deposition of amyloid in extracerebral tissues is very common and seems inevitable for an aging person. Most deposits are localized, small, and probably without consequence, but in some instances, they are associated with diseases such as type 2 diabetes. Other extracerebral amyloidoses are systemic, with life-threatening effects on the heart, kidneys, and other organs. Here, we review how amyloid may spread through seeding and whether transmission of amyloid diseases may occur between humans. We also discuss whether cross-seeding is important in the development of amyloidosis, focusing specifically on the amyloid proteins AA, transthyretin, and islet amyloid polypeptide (IAPP).

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 38 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 38 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 9 24%
Student > Ph. D. Student 5 13%
Student > Master 5 13%
Student > Doctoral Student 3 8%
Student > Bachelor 2 5%
Other 3 8%
Unknown 11 29%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 8 21%
Agricultural and Biological Sciences 6 16%
Pharmacology, Toxicology and Pharmaceutical Science 3 8%
Veterinary Science and Veterinary Medicine 2 5%
Chemistry 2 5%
Other 5 13%
Unknown 12 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 March 2021.
All research outputs
#8,537,346
of 25,382,440 outputs
Outputs from Cold Spring Harbor Perspectives in Medicine
#464
of 860 outputs
Outputs of similar age
#146,857
of 420,824 outputs
Outputs of similar age from Cold Spring Harbor Perspectives in Medicine
#27
of 42 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 860 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 19.0. This one is in the 40th percentile – i.e., 40% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 420,824 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.
We're also able to compare this research output to 42 others from the same source and published within six weeks on either side of this one. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.