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Positive symptoms associate with cortical thinning in the superior temporal gyrus via the ENIGMA Schizophrenia consortium

Overview of attention for article published in Acta Psychiatrica Scandinavica, March 2017
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (87th percentile)
  • Good Attention Score compared to outputs of the same age and source (73rd percentile)

Mentioned by

news
1 news outlet
policy
1 policy source
twitter
9 X users
wikipedia
2 Wikipedia pages

Citations

dimensions_citation
80 Dimensions

Readers on

mendeley
176 Mendeley
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Title
Positive symptoms associate with cortical thinning in the superior temporal gyrus via the ENIGMA Schizophrenia consortium
Published in
Acta Psychiatrica Scandinavica, March 2017
DOI 10.1111/acps.12718
Pubmed ID
Authors

E. Walton, D. P. Hibar, T. G. M. van Erp, S. G. Potkin, R. Roiz‐Santiañez, B. Crespo‐Facorro, P. Suarez‐Pinilla, N. E. M. Van Haren, S. M. C. de Zwarte, R. S. Kahn, W. Cahn, N. T. Doan, K. N. Jørgensen, T. P. Gurholt, I. Agartz, O. A. Andreassen, L. T. Westlye, I. Melle, A. O. Berg, L. Mørch‐Johnsen, A. Færden, L. Flyckt, H. Fatouros‐Bergman, Karolinska Schizophrenia Project Consortium, E. G. Jönsson, R. Hashimoto, H. Yamamori, M. Fukunaga, A. Preda, P. De Rossi, F. Piras, N. Banaj, V. Ciullo, G. Spalletta, R. E. Gur, R. C. Gur, D. H Wolf, T. D. Satterthwaite, L. M. Beard, I. E. Sommer, S. Koops, O. Gruber, A. Richter, B. Krämer, S. Kelly, G. Donohoe, C. McDonald, D. M. Cannon, A. Corvin, M. Gill, A. Di Giorgio, A. Bertolino, S. Lawrie, T. Nickson, H. C. Whalley, E. Neilson, V. D. Calhoun, P. M. Thompson, J. A. Turner, S. Ehrlich

Abstract

Based on the role of the superior temporal gyrus (STG) in auditory processing, language comprehension and self-monitoring, this study aimed to investigate the relationship between STG cortical thickness and positive symptom severity in schizophrenia. This prospective meta-analysis includes data from 1987 individuals with schizophrenia collected at seventeen centres around the world that contribute to the ENIGMA Schizophrenia Working Group. STG thickness measures were extracted from T1-weighted brain scans using FreeSurfer. The study performed a meta-analysis of effect sizes across sites generated by a model predicting left or right STG thickness with a positive symptom severity score (harmonized SAPS or PANSS-positive scores), while controlling for age, sex and site. Secondary models investigated relationships between antipsychotic medication, duration of illness, overall illness severity, handedness and STG thickness. Positive symptom severity was negatively related to STG thickness in both hemispheres (left: βstd = -0.052; P = 0.021; right: βstd = -0.073; P = 0.001) when statistically controlling for age, sex and site. This effect remained stable in models including duration of illness, antipsychotic medication or handedness. Our findings further underline the important role of the STG in hallmark symptoms in schizophrenia. These findings can assist in advancing insight into symptom-relevant pathophysiological mechanisms in schizophrenia.

X Demographics

X Demographics

The data shown below were collected from the profiles of 9 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 176 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 176 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 34 19%
Researcher 26 15%
Student > Master 21 12%
Student > Doctoral Student 12 7%
Student > Bachelor 8 5%
Other 25 14%
Unknown 50 28%
Readers by discipline Count As %
Psychology 36 20%
Neuroscience 29 16%
Medicine and Dentistry 18 10%
Biochemistry, Genetics and Molecular Biology 7 4%
Agricultural and Biological Sciences 4 2%
Other 9 5%
Unknown 73 41%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 17. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 July 2019.
All research outputs
#2,129,626
of 25,732,188 outputs
Outputs from Acta Psychiatrica Scandinavica
#348
of 2,938 outputs
Outputs of similar age
#39,131
of 324,128 outputs
Outputs of similar age from Acta Psychiatrica Scandinavica
#8
of 30 outputs
Altmetric has tracked 25,732,188 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,938 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.2. This one has done well, scoring higher than 88% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 324,128 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 30 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.