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Glucose principally regulates insulin secretion in mouse islets by controlling the numbers of granule fusion events per cell

Overview of attention for article published in Diabetologia, September 2013
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Title
Glucose principally regulates insulin secretion in mouse islets by controlling the numbers of granule fusion events per cell
Published in
Diabetologia, September 2013
DOI 10.1007/s00125-013-3019-5
Pubmed ID
Authors

Jiun T. Low, Justin M. Mitchell, Oanh H. Do, Jacinda Bax, Alicia Rawlings, Michael Zavortink, Garry Morgan, Robert G. Parton, Herbert Y. Gaisano, Peter Thorn

Abstract

In dispersed single beta cells the response of each cell to glucose is heterogeneous. In contrast, within an islet, cell-to-cell communication leads to glucose inducing a more homogeneous response. For example, increases in NAD(P)H and calcium are relatively uniform across the cells of the islet. These data suggest that secretion of insulin from single beta cells within an islet should also be relatively homogeneous. The aim of this study was to test this hypothesis by determining the glucose dependence of single-cell insulin responses within an islet.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 44 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
Unknown 43 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 10 23%
Researcher 7 16%
Student > Doctoral Student 4 9%
Other 4 9%
Student > Master 3 7%
Other 6 14%
Unknown 10 23%
Readers by discipline Count As %
Agricultural and Biological Sciences 10 23%
Biochemistry, Genetics and Molecular Biology 7 16%
Engineering 4 9%
Medicine and Dentistry 3 7%
Neuroscience 2 5%
Other 6 14%
Unknown 12 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 October 2013.
All research outputs
#18,351,676
of 22,727,570 outputs
Outputs from Diabetologia
#4,672
of 5,031 outputs
Outputs of similar age
#149,733
of 200,191 outputs
Outputs of similar age from Diabetologia
#44
of 50 outputs
Altmetric has tracked 22,727,570 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,031 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 22.6. This one is in the 3rd percentile – i.e., 3% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 200,191 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 50 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.