Title |
Whole genome methylation array analysis reveals new aspects in Balkan endemic nephropathy etiology
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Published in |
BMC Nephrology, October 2013
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DOI | 10.1186/1471-2369-14-225 |
Pubmed ID | |
Authors |
Rada Staneva, Blaga Rukova, Savina Hadjidekova, Desislava Nesheva, Olga Antonova, Plamen Dimitrov, Valeri Simeonov, Georgi Stamenov, Rade Cukuranovic, Jovana Cukuranovic, Vladislav Stefanovic, Momir Polenakovic, Ivanka Dimova, Ruslan Hlushchuk, Valentin Djonov, Angel Galabov, Draga Toncheva |
Abstract |
Balkan endemic nephropathy (BEN) represents a chronic progressive interstitial nephritis in striking correlation with uroepithelial tumours of the upper urinary tract. The disease has endemic distribution in the Danube river regions in several Balkan countries.DNA methylation is a primary epigenetic modification that is involved in major processes such as cancer, genomic imprinting, gene silencing, etc. The significance of CpG island methylation status in normal development, cell differentiation and gene expression is widely recognized, although still stays poorly understood. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
India | 1 | 4% |
Unknown | 24 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 5 | 20% |
Student > Ph. D. Student | 5 | 20% |
Student > Doctoral Student | 4 | 16% |
Professor > Associate Professor | 3 | 12% |
Researcher | 3 | 12% |
Other | 3 | 12% |
Unknown | 2 | 8% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 6 | 24% |
Agricultural and Biological Sciences | 5 | 20% |
Medicine and Dentistry | 5 | 20% |
Immunology and Microbiology | 2 | 8% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 4% |
Other | 3 | 12% |
Unknown | 3 | 12% |