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The Application of Nanomaterials in Stem Cell Therapy for Some Neurological Diseases.

Overview of attention for article published in Current Drug Targets, February 2018
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Title
The Application of Nanomaterials in Stem Cell Therapy for Some Neurological Diseases.
Published in
Current Drug Targets, February 2018
DOI 10.2174/1389450118666170328115801
Pubmed ID
Authors

Guilong Zhang, Ahsan Ali Khan, Hao Wu, Lukui Chen, Yuchun Gu, Ning Gu

Abstract

Stem cell therapy provides great promising therapeutic benefits for various neurological disorders. Cell transplantation has emerged as cell replacement application for nerve damage. Recently, nanomaterials obtain wide development in various industrial and medical fields, and nanoparticles have been applied to neuro-medical field for tracking and treating nervous system diseases. Combining stem cell with nanotechnology has raised more and more attentions; and it has demonstrated that it has huge effects on clinical diagnosis and therapeutics in multiple central nervous system diseases, meanwhile, improving prognosis. This review gives a brief overview of the application of nanomaterials in stem cell therapy for neurological diseases. Nanoparticles not only promote stem cell proliferation and differentiation in vitro or in vivo, but also play dominant roles in stem cell imaging and tracking. Furthermore, via delivering genes or drugs, nanoparticles can participate in stem cell therapeutic applications for various neurological diseases, such as ischemic stroke, spinal cord injury (SCI), multiple sclerosis (MS), Parkinson's disease (PD), Alzheimer's disease (AD) and gliomas. However, nanoparticles have potential cytotoxic effects on nerve cells, which are related to their physicochemical properties. Above all, nano-stem cell-based therapy as a promising strategy has the ability to affect neuronal repair and regeneration in the central nervous system.

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X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 60 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 60 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 9 15%
Student > Bachelor 7 12%
Researcher 6 10%
Student > Ph. D. Student 5 8%
Student > Postgraduate 4 7%
Other 7 12%
Unknown 22 37%
Readers by discipline Count As %
Medicine and Dentistry 12 20%
Biochemistry, Genetics and Molecular Biology 6 10%
Agricultural and Biological Sciences 4 7%
Neuroscience 3 5%
Chemistry 2 3%
Other 9 15%
Unknown 24 40%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 March 2017.
All research outputs
#14,918,049
of 25,382,440 outputs
Outputs from Current Drug Targets
#631
of 1,121 outputs
Outputs of similar age
#229,450
of 447,760 outputs
Outputs of similar age from Current Drug Targets
#23
of 74 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one is in the 40th percentile – i.e., 40% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,121 research outputs from this source. They receive a mean Attention Score of 4.7. This one is in the 43rd percentile – i.e., 43% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 447,760 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 74 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.