| Title |
Agricultural activities and the incidence of Parkinson’s disease in the general French population
|
|---|---|
| Published in |
European Journal of Epidemiology, February 2017
|
| DOI | 10.1007/s10654-017-0229-z |
| Pubmed ID | |
| Authors |
Sofiane Kab, Johan Spinosi, Laura Chaperon, Aline Dugravot, Archana Singh-Manoux, Frédéric Moisan, Alexis Elbaz |
| Abstract |
Most studies on pesticides and Parkinson's disease (PD) focused on occupational exposure in farmers. Whether non-occupational exposure is associated with PD has been little explored. We investigated the association between agricultural characteristics and PD incidence in a French nationwide ecologic study. We hypothesized that persons living in regions with agricultural activities involving more intensive pesticide use would be at higher risk. We identified incident PD cases from French National Health Insurance databases (2010-2012). The proportion of land dedicated to 18 types of agricultural activities was defined at the canton of residence level. We examined the association between agricultural activities and PD age/sex-standardized incidence ratios using multivariable multilevel Poisson regression adjusted for smoking, deprivation index, density of neurologists, and rurality (proportion of agricultural land); we used a false discovery rate approach to correct for multiple comparisons and compute q-values. We also compared incidence in clusters of cantons with similar agricultural characteristics (k-means algorithm). We identified 69,010 incident PD cases. Rurality was associated with higher PD incidence (p < 0.001). Cantons with higher density of vineyards displayed the strongest association (RRtop/bottom quartile = 1.102, 95% CI = 1.049-1.158; q-trend = 0.040). This association was similar in men, women, and non-farmers, stronger in older than younger persons, and present in all French regions. Persons living in the cluster with greatest vineyards density had 8.5% (4.4-12.6%) higher PD incidence (p < 0.001). In France, vineyards rank among the crops that require most intense pesticide use. Regions with greater presence of vineyards are characterized by higher PD risk; non-professional pesticides exposure is a possible explanation. |
X Demographics
The data shown below were collected from the profiles of 31 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| France | 4 | 13% |
| Netherlands | 3 | 10% |
| Latvia | 2 | 6% |
| Switzerland | 2 | 6% |
| United Kingdom | 1 | 3% |
| Martinique | 1 | 3% |
| United States | 1 | 3% |
| Belgium | 1 | 3% |
| Unknown | 16 | 52% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 29 | 94% |
| Scientists | 2 | 6% |
Mendeley readers
The data shown below were compiled from readership statistics for 84 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 84 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 10 | 12% |
| Student > Bachelor | 9 | 11% |
| Other | 8 | 10% |
| Student > Doctoral Student | 7 | 8% |
| Student > Master | 7 | 8% |
| Other | 13 | 15% |
| Unknown | 30 | 36% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 11 | 13% |
| Neuroscience | 9 | 11% |
| Agricultural and Biological Sciences | 6 | 7% |
| Nursing and Health Professions | 5 | 6% |
| Environmental Science | 5 | 6% |
| Other | 12 | 14% |
| Unknown | 36 | 43% |
Attention Score in Context
This research output has an Altmetric Attention Score of 40. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 March 2024.
All research outputs
#1,052,953
of 25,734,859 outputs
Outputs from European Journal of Epidemiology
#156
of 1,816 outputs
Outputs of similar age
#22,587
of 426,729 outputs
Outputs of similar age from European Journal of Epidemiology
#4
of 22 outputs
Altmetric has tracked 25,734,859 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,816 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 37.7. This one has done particularly well, scoring higher than 91% of its peers.
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We're also able to compare this research output to 22 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 81% of its contemporaries.