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Alcohol consumption and risk of upper-tract urothelial cancer

Overview of attention for article published in Cancer Epidemiology, March 2017
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2 X users
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1 peer review site

Citations

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19 Dimensions

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32 Mendeley
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Title
Alcohol consumption and risk of upper-tract urothelial cancer
Published in
Cancer Epidemiology, March 2017
DOI 10.1016/j.canep.2017.03.002
Pubmed ID
Authors

Masayoshi Zaitsu, Ichiro Kawachi, Takumi Takeuchi, Yasuki Kobayashi

Abstract

Upper-tract urothelial cancer (UTUC), which includes renal pelvic cancer and ureter cancer, is a rare cancer and its prognosis is poor. Smoking and high-risk occupations (e.g., printing and dyestuff working which involves exposure to aniline dyes) are well-known risk factors for UTUC. However, the risk of alcohol consumption in UTUC remains unclear. This study aimed to determine whether alcohol consumption is an independent risk factor for UTUC. The study was a case-control study which used the nationwide clinical inpatient database of the Rosai Hospital group in Japan. We identified 1569 cases and 506,797 controls between 1984 and 2014. We estimated the odds ratio (OR) and 95% confidence interval (95%CI) of alcohol consumption for UTUC - never, up to 15g/day, >15-30g/day, or >30g/day - using unconditional logistic regression. We adjusted for the following covariates: age, sex, study period, hospital, history of smoking, and high-risk occupation. The risk of UTUC was significantly higher in ever-drinkers compared with never-drinkers (OR=1.23, 95%CI, 1.08-1.40; P=0.001). Compared with never-drinkers, the risk threshold for UTUC was >15g of alcohol consumption per day (equivalent to 6 ounces of Japanese sake containing 23g of alcohol). A dose-response was observed (P<0.001). Alcohol consumption may be an independent risk factor for UTUC, with a low-risk threshold of 15g of alcohol per day.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 32 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 8 25%
Student > Master 4 13%
Student > Bachelor 4 13%
Student > Ph. D. Student 3 9%
Student > Doctoral Student 1 3%
Other 1 3%
Unknown 11 34%
Readers by discipline Count As %
Medicine and Dentistry 11 34%
Engineering 2 6%
Social Sciences 2 6%
Nursing and Health Professions 1 3%
Agricultural and Biological Sciences 1 3%
Other 3 9%
Unknown 12 38%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 July 2017.
All research outputs
#15,173,117
of 25,382,440 outputs
Outputs from Cancer Epidemiology
#806
of 1,434 outputs
Outputs of similar age
#170,240
of 323,203 outputs
Outputs of similar age from Cancer Epidemiology
#7
of 14 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one is in the 38th percentile – i.e., 38% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,434 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.5. This one is in the 42nd percentile – i.e., 42% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 323,203 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.