Title |
Link Between Oxidative Stress and Acute Brain Ischemia
|
---|---|
Published in |
Angiology, October 2013
|
DOI | 10.1177/0003319713506516 |
Pubmed ID | |
Authors |
Djordje Radak, Ivana Resanovic, Esma R. Isenovic |
Abstract |
The pathogenesis of acute brain ischemia (ABI) is highly complex and involves multiple mechanisms including free radical generation. Imbalance between the cellular production of free radicals and the ability of cells to defend against them is referred to as oxidative stress. Oxidative stress is one of the mechanisms contributing to neuronal damage, potentially induced through the ABI. Through interactions with a large number of molecules, reactive oxygen species may irreversibly destroy or alter the function of the cellular lipids, proteins, and nucleic acids and initiate cell signaling pathways after cerebral ischemia. Future investigations should focus on the understanding of oxidative stress mechanisms and neuroprotection in order to discover new treatment targets. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 1 | 2% |
Canada | 1 | 2% |
Unknown | 41 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 7 | 16% |
Student > Master | 6 | 14% |
Student > Doctoral Student | 5 | 12% |
Student > Bachelor | 5 | 12% |
Professor | 3 | 7% |
Other | 10 | 23% |
Unknown | 7 | 16% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 8 | 19% |
Agricultural and Biological Sciences | 7 | 16% |
Neuroscience | 6 | 14% |
Biochemistry, Genetics and Molecular Biology | 5 | 12% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 5% |
Other | 5 | 12% |
Unknown | 10 | 23% |