Title |
Coexistent Multiple Myeloma or Increased Bone Marrow Plasma Cells Define Equally High-Risk Populations in Patients With Immunoglobulin Light Chain Amyloidosis
|
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Published in |
Journal of Clinical Oncology, October 2013
|
DOI | 10.1200/jco.2013.50.8499 |
Pubmed ID | |
Authors |
Taxiarchis V. Kourelis, Shaji K. Kumar, Morie A. Gertz, Martha Q. Lacy, Francis K. Buadi, Suzanne R. Hayman, Steven Zeldenrust, Nelson Leung, Robert A. Kyle, Stephen Russell, David Dingli, John A. Lust, Yi Lin, Prashant Kapoor, S. Vincent Rajkumar, Arleigh McCurdy, Angela Dispenzieri |
Abstract |
There is consensus that patients with light chain (AL) amyloidosis with hypercalcemia, renal failure, anemia, and lytic bone lesions attributable to clonal expansion of plasma cells (CRAB criteria) also have multiple myeloma (MM). The aim of this study was to examine the spectrum of immunoglobulin AL amyloidosis with and without MM, with a goal of defining the optimal bone marrow plasma cell (BMPC) number to qualify as AL amyloidosis with MM. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 11 | 55% |
France | 1 | 5% |
Spain | 1 | 5% |
Morocco | 1 | 5% |
Unknown | 6 | 30% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 11 | 55% |
Scientists | 5 | 25% |
Practitioners (doctors, other healthcare professionals) | 3 | 15% |
Science communicators (journalists, bloggers, editors) | 1 | 5% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | <1% |
Unknown | 156 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 28 | 18% |
Researcher | 18 | 11% |
Other | 17 | 11% |
Student > Ph. D. Student | 12 | 8% |
Student > Postgraduate | 10 | 6% |
Other | 33 | 21% |
Unknown | 39 | 25% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 67 | 43% |
Agricultural and Biological Sciences | 10 | 6% |
Nursing and Health Professions | 9 | 6% |
Biochemistry, Genetics and Molecular Biology | 7 | 4% |
Unspecified | 3 | 2% |
Other | 22 | 14% |
Unknown | 39 | 25% |