Title |
Prevention or acceleration of type 1 diabetes by viruses
|
---|---|
Published in |
Cellular and Molecular Life Sciences, July 2012
|
DOI | 10.1007/s00018-012-1042-1 |
Pubmed ID | |
Authors |
Liana Ghazarian, Julien Diana, Yannick Simoni, Lucie Beaudoin, Agnès Lehuen |
Abstract |
Type 1 diabetes is an autoimmune disease characterized by the destruction of insulin-producing pancreatic β-cells. Even though extensive scientific research has yielded important insights into the immune mechanisms involved in pancreatic β-cell destruction, little is known about the events that trigger the autoimmune process. Recent epidemiological and experimental data suggest that environmental factors are involved in this process. In this review, we discuss the role of viruses as an environmental factor on the development of type 1 diabetes, and the immune mechanisms by which they can trigger or protect against this pathology. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 4% |
Unknown | 52 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 10 | 19% |
Student > Master | 10 | 19% |
Student > Ph. D. Student | 7 | 13% |
Student > Doctoral Student | 4 | 7% |
Student > Bachelor | 2 | 4% |
Other | 9 | 17% |
Unknown | 12 | 22% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 13 | 24% |
Medicine and Dentistry | 9 | 17% |
Biochemistry, Genetics and Molecular Biology | 6 | 11% |
Immunology and Microbiology | 4 | 7% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 4% |
Other | 6 | 11% |
Unknown | 14 | 26% |