| Title |
Transepidermal water loss in young and aged healthy humans: a systematic review and meta-analysis
|
|---|---|
| Published in |
Archives of Dermatological Research, January 2013
|
| DOI | 10.1007/s00403-012-1313-6 |
| Pubmed ID | |
| Authors |
Jan Kottner, Andrea Lichterfeld, Ulrike Blume-Peytavi |
| Abstract |
Transepidermal water loss (TEWL) is regarded as one of the most important parameters for characterizing skin barrier function but an agreed upon definition of what a "normal" TEWL is does not exist. In order to determine generalizable TEWL values for healthy adults, a systematic review and meta-analysis was conducted. The databases MEDLINE and EMBASE and publication lists were screened. After full-text appraisal of 398 studies, 231 studies were excluded due to unclear or insufficient reporting. 167 studies providing data about 50 skin areas were included in the final data synthesis. Pooled sample sizes ranged from n = 5 for the left cheek and the left lower back to a maximum of n = 2,838 for the right midvolar forearm area. The lowest TEWL of 2.3 (95 % CI 1.9-2.7) g/m(2)/h was calculated for the breast skin, the highest TEWL of 44.0 (39.8-48.2) g/m(2)/h for the axilla. TEWL in individuals being 65 years and above was consistently lower compared to the group of 18- to 64-year-old individuals. The quality of reporting TEWL in humans should be increased in future studies. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 50% |
| Members of the public | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 139 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 1% |
| Austria | 2 | 1% |
| Spain | 1 | <1% |
| Japan | 1 | <1% |
| Unknown | 133 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 19 | 14% |
| Researcher | 19 | 14% |
| Student > Master | 17 | 12% |
| Student > Bachelor | 16 | 12% |
| Student > Postgraduate | 12 | 9% |
| Other | 22 | 16% |
| Unknown | 34 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 46 | 33% |
| Chemistry | 10 | 7% |
| Engineering | 9 | 6% |
| Pharmacology, Toxicology and Pharmaceutical Science | 7 | 5% |
| Nursing and Health Professions | 7 | 5% |
| Other | 23 | 17% |
| Unknown | 37 | 27% |
Attention Score in Context
This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 December 2022.
All research outputs
#4,151,279
of 23,392,375 outputs
Outputs from Archives of Dermatological Research
#135
of 1,357 outputs
Outputs of similar age
#44,207
of 283,792 outputs
Outputs of similar age from Archives of Dermatological Research
#2
of 13 outputs
Altmetric has tracked 23,392,375 research outputs across all sources so far. Compared to these this one has done well and is in the 82nd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,357 research outputs from this source. They receive a mean Attention Score of 5.0. This one has done well, scoring higher than 89% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 283,792 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 84% of its contemporaries.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 84% of its contemporaries.